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  • Product Name: Biapenem
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120410-24-4

120410-24-4 structure
120410-24-4 structure
  • Name: Biapenem
  • Chemical Name: biapenem
  • CAS Number: 120410-24-4
  • Molecular Formula: C15H18N4O4S
  • Molecular Weight: 350.393
  • Catalog: API Synthetic anti-infective drugs Antifungal drugs
  • Create Date: 2018-05-11 08:00:00
  • Modify Date: 2024-01-02 13:14:21
  • Biapenem is a parenteral carbapenem antibacterial agent with a broad spectrum.Target: AntibacterialBiapenem is a carbapenem antibiotic of in vitro antibacterial activity encompassing many Gramnegative and Gram-positive aerobic and anaerobic bacteria, including species producing β-lactamases. Biapenem is more stable than imipenem, mero-penem and panipenem to hydrolysis by human renal dihydropeptidase-I (DHP-I), and therefore does not require the coadministration of a DHP-I inhibitor. In randomised, nonblind or double-blind clinical trials, biapenem showed good clinical and bacteriological efficacy (similar to that of imipenem/ cilastatin) in the treatment of adult patients with intra-abdominal infections, lower respiratory infections or complicated urinary tract infections.
Name biapenem
Synonyms Biapenem (JAN/USAN)
EINECS 204-352-8
5H-Pyrazolo[1,2-a][1,2,4]triazol-4-ium, 6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-, inner salt
BiapeneM Crude
Biapenem [USAN:INN]
(4R,5S,6S)-3-(6,7-Dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
[4R-[4a,5b,6b(R*)]]-6-[[2-Carboxy-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5 H-pyrazolo[1,2-a][1,2,4]triazol-4-ium inner salt
LJ C10627
omegacin
MFCD00864863
Biapenem
LJ C10,627
Biapenern
L-627
Description Biapenem is a parenteral carbapenem antibacterial agent with a broad spectrum.Target: AntibacterialBiapenem is a carbapenem antibiotic of in vitro antibacterial activity encompassing many Gramnegative and Gram-positive aerobic and anaerobic bacteria, including species producing β-lactamases. Biapenem is more stable than imipenem, mero-penem and panipenem to hydrolysis by human renal dihydropeptidase-I (DHP-I), and therefore does not require the coadministration of a DHP-I inhibitor. In randomised, nonblind or double-blind clinical trials, biapenem showed good clinical and bacteriological efficacy (similar to that of imipenem/ cilastatin) in the treatment of adult patients with intra-abdominal infections, lower respiratory infections or complicated urinary tract infections.
Related Catalog
References

[1]. Perry, C.M. and T. Ibbotson, Biapenem. Drugs, 2002. 62(15): p. 2221-34; discussion 2235.

[2]. Kasahara, S., et al., [Clinical effects of biapenem on febrile neutropenia in patients with hematological malignancy]. Jpn J Antibiot, 2008. 61(3): p. 115-21.
Melting Point 265-271°C (dec.)
Molecular Formula C15H18N4O4S
Molecular Weight 350.393
Exact Mass 350.104889
PSA 127.67000
Index of Refraction 1.651
Storage condition -20?C Freezer
RIDADR NONH for all modes of transport
Precursor  2

DownStream  0


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title: CAS No. 120410-24-4 | Chemsrc address: https://m.chemsrc.com/en/baike/237849.html

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