133550-18-2
133550-18-2 structure
- Name: AG 538
- Chemical Name: Tyrphostin AG 538
- CAS Number: 133550-18-2
- Molecular Formula: C16H11NO5
- Molecular Weight: 297.262
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK IGF-1R
- Create Date: 2017-01-02 14:33:58
- Modify Date: 2025-08-25 20:38:53
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AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC50 of 400 nM[1].
| Name | Tyrphostin AG 538 |
|---|---|
| Synonyms |
AGS 199
(2E)-2-(3,4-Dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)acrylonitrile AG538 Benzenepropanenitrile, α-[(3,4-dihydroxyphenyl)methylene]-3,4-dihydroxy-β-oxo-, (αE)- AG 538 3,4-dihydroxy-α-(3,4-dihydroxybenzoyl)-cis-cinnamonitrile tyrphostin AG 538 |
| Description | AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC50 of 400 nM[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 637.5±55.0 °C at 760 mmHg |
| Molecular Formula | C16H11NO5 |
| Molecular Weight | 297.262 |
| Flash Point | 339.3±31.5 °C |
| Exact Mass | 297.063721 |
| PSA | 121.78000 |
| LogP | 1.79 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.754 |