119584-70-2

119584-70-2 structure
119584-70-2 structure

Name 5-Fluoro-2,4-diaminoquinazoline
Synonyms 5-fluoroquinazoline-2,4-diamine
2,4-Quinazolinediamine, 5-fluoro-
MFCD00221785
5-Fluoro-2,4-quinazolinediamine
2,4-Diamino-5-fluoroquinazoline
Density 1.5±0.1 g/cm3
Boiling Point 463.1±53.0 °C at 760 mmHg
Melting Point 245-248°C
Molecular Formula C8H7FN4
Molecular Weight 178.166
Flash Point 233.9±30.9 °C
Exact Mass 178.065475
PSA 77.82000
LogP 1.01
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.757

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA1367730
CHEMICAL NAME :
2,4-Quinazolinediamine, 5-fluoro-
CAS REGISTRY NUMBER :
119584-70-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H7-F-N4
MOLECULAR WEIGHT :
178.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
489 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,434,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,434,1990
Hazard Codes Xi: Irritant;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36
RTECS VA1367730
HS Code 2933990090

~91%

119584-70-2 structure

119584-70-2

Literature: Hynes, John B.; Pathak, Alpana; Panos, Constantina H.; Okeke, Claudia C. Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1173 - 1177

~35%

119584-70-2 structure

119584-70-2

Literature: Harris, Neil V.; Smith, Christopher; Bowden, Keith Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 434 - 444

~16%

119584-70-2 structure

119584-70-2

Literature: Journal of Heterocyclic Chemistry, , vol. 29, # 4 p. 915 - 920
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%