5-Fluoro-2,4-quinazolinediamine

Modify Date: 2025-09-02 17:13:54

5-Fluoro-2,4-quinazolinediamine structure	Common Name	5-Fluoro-2,4-quinazolinediamine
	CAS Number	119584-70-2	Molecular Weight	178.166
	Density	1.5±0.1 g/cm3	Boiling Point	463.1±53.0 °C at 760 mmHg
	Molecular Formula	C₈H₇FN₄	Melting Point	245-248°C
	MSDS	N/A	Flash Point	233.9±30.9 °C

Name	5-Fluoro-2,4-diaminoquinazoline
Synonym	More Synonyms

Density	1.5±0.1 g/cm3
Boiling Point	463.1±53.0 °C at 760 mmHg
Melting Point	245-248°C
Molecular Formula	C₈H₇FN₄
Molecular Weight	178.166
Flash Point	233.9±30.9 °C
Exact Mass	178.065475
PSA	77.82000
LogP	1.01
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.757
InChIKey	ZFIDHZVBIBPRBQ-UHFFFAOYSA-N
SMILES	Nc1nc(N)c2c(F)cccc2n1

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA1367730

CHEMICAL NAME :: 2,4-Quinazolinediamine, 5-fluoro-

CAS REGISTRY NUMBER :: 119584-70-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H7-F-N4

MOLECULAR WEIGHT :: 178.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 489 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,434,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,434,1990

Hazard Codes	Xi: Irritant;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36
RTECS	VA1367730
HS Code	2933990090

2,6-Difluoroben...

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carbonic acid; ...

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~91%

5-Fluoro-2,4-qu...

CAS#:119584-70-2

Literature: Hynes, John B.; Pathak, Alpana; Panos, Constantina H.; Okeke, Claudia C. Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1173 - 1177

Chloroformamidi...

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2-Amino-6-fluor...

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~35%

5-Fluoro-2,4-qu...

CAS#:119584-70-2

Literature: Harris, Neil V.; Smith, Christopher; Bowden, Keith Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 434 - 444

Carbonic acid-g...

CAS#:593-85-1

2-Fluoro-6-nitr...

CAS#:143306-27-8

~16%

5-Nitroquinazol...

CAS#:123241-89-4

5-Fluoro-2,4-qu...

CAS#:119584-70-2

Literature: Journal of Heterocyclic Chemistry, , vol. 29, # 4 p. 915 - 920

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Name: Acute toxicity determined in mice by an LD50 test when administered perorally
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL877795

Name: Antiviral activity against Dengue virus 2 infected in BHK-D2RepT replicon systems ass...
Source: ChEMBL
Target: dengue virus type 2
External Id: CHEMBL2044697

Name: Acute toxicity determined in mice by an LD50 test when administered intraperitoneally
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL738035

Name: Antibacterial activity (10 e-6 log (1/MIC) towards Escherichia coli
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL675030

Name: Partition coefficient (logP)
Source: ChEMBL
Target: N/A
External Id: CHEMBL634042

Name: In vitro inhibition of Staphylococcus aureus (NTCT6571A) Dihydrofolate reductase.
Source: ChEMBL
Target: Dihydrofolate reductase
External Id: CHEMBL665874

Name: Cytotoxicity against hamster BHK cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL2044698

Name: In vitro inhibition of Escherichia coli (B41) Dihydrofolate reductase.
Source: ChEMBL
Target: Dihydrofolate reductase
External Id: CHEMBL668340

Name: In vitro inhibition of Bovine liver dihydrofolate reductase.
Source: ChEMBL
Target: Dihydrofolate reductase
External Id: CHEMBL669349

Name: Dissociation constant was determined using UV method
Source: ChEMBL
Target: N/A
External Id: CHEMBL632412

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5-fluoroquinazoline-2,4-diamine

MFCD00221785

5-Fluoro-2,4-quinazolinediamine

2,4-Diamino-5-fluoroquinazoline

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-Fluoro-2,4-quinazolinediamine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,4-diamino-5-fluoroquinazoline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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5-Fluoro-2,4-quinazolinediamine

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Customs

5-Fluoro-2,4-quinazolinediamineBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.