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136587-13-8

136587-13-8 structure

136587-13-8 structure

Name: Spermine NONOate
Chemical Name: Spermine Bis (Nitric Oxide) Adduct
CAS Number: 136587-13-8
Molecular Formula: C₁₀H₂₆N₆O₂
Molecular Weight: 262.352
Catalog: Research Areas Others
Create Date: 2018-09-01 11:21:01
Modify Date: 2026-06-30 20:24:34
Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing[1].

Name	Spermine Bis (Nitric Oxide) Adduct
Synonyms	SPERMINE BIS (NITRIC OXIDE) ADDUCT (Z)-1-[N-[3-AMINOPROPYL]-N-[4-(3-AMINOPROPYL-AMMONIO)BUTYL]-AMINO]-DIAZEN-1-IUM-1,2-DIOLATE N-[3-aminopropyl-[4-(3-aminopropylamino)butyl]amino]-N-hydroxynitrous amide Spermine Bis(NO) Adduct 1-(3-Aminopropyl)-1-{4-[(3-aminopropyl)amino]butyl}-2-hydroxy-3-oxotriazane SPERMINE/NITRIC OXIDE COMPLEX Spermine-Nitric oxide complex hydrate SPER/NO, Spermine NONOate, N-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazino]butyl]-1,3-propanediamine N'-(3-Aminopropyl)-N'-(4-((3-aminopropyl)amino)butyl)-N-hydroxynitrous hydrazide SPERMINE NONOATE Spermine NONOate - - Calbiochem N-(2-AMINOETHYL)-N-(2-HYDROXY-2-NITROSOHYDRAZINO)-1,2-ETHYLENEDIAMINE N-(2-AMINOETHYL)-N-(2-HYDROXY-3-NITROSOHYDRAZINO)-1,2-ETHYLENEDIAMINE N1-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazinyl]butyl]-1,3-propanediamine N'-(3-aMinopropyl)-N'-(4-((3-aMinopropyl)amino)butyl)-N-hydroxynitrous hydrazide hydrate (Z)-1-[N-(3-AMMONIOPROPYL)-N-[4-(3-AMINOPROPYLAMMONIO) BUTYL]-AMINO]DIAZEN-1-IUM-1,2-DIOLATE SPERMINE/NITRIC OXIDE COMPLEX (SPER/NO) NOC-22 1,3-Propanediamine, N1-[4-[1-(3-aminopropyl)-2-hydroxy-2-nitrosohydrazinyl]butyl] SPER/NO SpermineNONOate,SPER/NO N-[4-[1-(3-AMINOPROPYL)-2-HYDROXY-2-NITROSOHYDRAZINO]BUTYL]-1,3-PROPANEDIAMINE

Description	Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Spermine NONOate has a half-life of 39 minutes and 230 minutes at 37°C and 22-25°C, respectively[1].
References	[1]. A Ramamurthi , et al. Measurement and modeling of nitric oxide release rates for nitric oxide donors. Chem Res Toxicol. 1997 Apr;10(4):408-13. [2]. K Homer, et al. In vitro comparison of two NONOates (novel nitric oxide donors) on rat pulmonary arteries. Eur J Pharmacol. 1998 Aug 28;356(1):49-57.

Density	1.2±0.1 g/cm3
Boiling Point	425.4±55.0 °C at 760 mmHg
Melting Point	105-107ºC
Molecular Formula	C₁₀H₂₆N₆O₂
Molecular Weight	262.352
Flash Point	211.1±31.5 °C
Exact Mass	262.211731
PSA	120.21000
LogP	-1.03
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.554

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22;S24/25
RIDADR	NONH for all modes of transport
HS Code	2928000090

71-44-3 structure

71-44-3

~35%

136587-13-8 structure

136587-13-8

Literature: Maragos, Chris M.; Morley, Deborah; Wink, David A.; Dunamas, Tambra M.; Saavedra, Joseph E.; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 11 p. 3242 - 3247

Precursor 1
71-44-3
DownStream 0

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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