205432-12-8
205432-12-8 structure
- Name: JS-K
- Chemical Name: (Z)-(2,4-dinitrophenoxy)imino-(4-ethoxycarbonylpiperazin-1-yl)-oxidoazanium
- CAS Number: 205432-12-8
- Molecular Formula: C13H16N6O8
- Molecular Weight: 384.30200
- Create Date: 2017-07-31 12:12:32
- Modify Date: 2025-08-25 21:34:55
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JS-K is a NO donor that reacts with glutathione to generate NO at physiological pH[1]. JS-K inhibits proliferation, induces apoptosis, and disrupts the cell cycle of Jurkat T acute lymphoblastic leukemia cells[2].
| Name | (Z)-(2,4-dinitrophenoxy)imino-(4-ethoxycarbonylpiperazin-1-yl)-oxidoazanium |
|---|---|
| Synonyms |
HMS3261L12
O2-(2,4-Dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate JS-K |
| Description | JS-K is a NO donor that reacts with glutathione to generate NO at physiological pH[1]. JS-K inhibits proliferation, induces apoptosis, and disrupts the cell cycle of Jurkat T acute lymphoblastic leukemia cells[2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.606g/cm3 |
|---|---|
| Boiling Point | 546.692ºC at 760 mmHg |
| Molecular Formula | C13H16N6O8 |
| Molecular Weight | 384.30200 |
| Flash Point | 284.429ºC |
| Exact Mass | 384.10300 |
| PSA | 174.76000 |
| LogP | 2.89380 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.656 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | TL1364200 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
