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35834-26-5

35834-26-5 structure

35834-26-5 structure

Name: rosamicin
Chemical Name: rosaramicin
CAS Number: 35834-26-5
Molecular Formula: C₃₁H₅₁NO₉
Molecular Weight: 581.73800
Catalog: API Antibiotics Aminoglycoside
Create Date: 2018-09-06 19:46:34
Modify Date: 2026-07-16 11:05:00

Name	rosaramicin
Synonyms	antibiotic antibioticm4365a2 12,16-tetramethyl-5,13-dioxo-9-((3,4,6-trideoxy-3-(dimethylamino)-beta-d-xylo Antibiotic 67-694 ROSAMICIN //BP rosamicin from micromonospora rosia sch14947 Rosaramicine [INN-French] JuvenimicinA3, Rosamicin Rosaramicinum [INN-Latin] frommicromonosporosia Rosaramicina [INN-Spanish] 2-[(14E)-9-[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-3-ethyl-7-hydroxy-2,8,12,16-tetramethyl-5,13-dioxo-4,17-dioxabicyclo[14.1.0]heptadec-14-en-10-yl]acetaldehyde 4'-DeoxyCirramycin A1 Cirramycin A1,4'-deoxy Juvenimicin A3 JUVENIMICIN A3 4’-deoxycirramycina(sub1) 4’-deoxy-cirramycina(sub1 4,17-dioxabicyclo(14.1.0)htadec-14-ene-10-acetaldehyde,3-ethyl-7-hydroxy-2,8 Juvenimicin A3 Rosaramicin Cirramycin A1, 4'-deoxy Antibiotic M 4365A2 m-4365a2 hexopyranosyl)oxy) Rosaramicin ROSAMICIN rosamycin M-4365A2 M4365A2 Rosamicin Micromonospora rosia

Density	1.17g/cm3
Boiling Point	734.7ºC at 760mmHg
Melting Point	119-122°
Molecular Formula	C₃₁H₅₁NO₉
Molecular Weight	581.73800
Flash Point	398.1ºC
Exact Mass	581.35600
PSA	135.13000
LogP	2.67040
Index of Refraction	1.532

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JG6800000

CHEMICAL NAME :: 4,17-Dioxabicyclo(14.1.0)heptadec-14-ene-10-acetaldeh yde, 3-ethyl-7-hydroxy-2,8,12,16- tetramethyl-5,13-dioxo-9-((3,4,6-trideoxy-3-(dimethyl amino)-beta-D-xylo-he xopyranosyl)oxy)-

CAS REGISTRY NUMBER :: 35834-26-5

LAST UPDATED :: 199509

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C31-H51-N-O9

MOLECULAR WEIGHT :: 581.83

WISWESSER LINE NOTATION :: T3-16- BO FOV OV PUTJ A1 D1 E2 IQ J1 L1VH N1 KO- BT6OTJ CQ DN1&1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,647,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 43,938,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 625 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,641,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 155 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,641,1972 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 4800 mg/kg/30D-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 3,129,1983

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	20/21/22
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	JG6800000

102438-11-9 structure

102438-11-9

~69%

35834-26-5 structure

35834-26-5

Literature: Fishman, Andrew G.; Mallams, Alan K.; Rossman, Randall R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 787 - 798

61486-91-7 structure

61486-91-7

~%

35834-26-5 structure

35834-26-5

Literature: Fishman, Andrew G.; Mallams, Alan K.; Rossman, Randall R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 787 - 798

122825-80-3 structure

122825-80-3

~%

35834-26-5 structure

35834-26-5

Literature: Fishman, Andrew G.; Mallams, Alan K.; Rossman, Randall R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 787 - 798

Precursor 3
102438-11-9 61486-91-7 122825-80-3
DownStream 2
56689-42-0 61486-91-7

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