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145-15-3

145-15-3 structure
145-15-3 structure
  • Name: 20(R)-Hydroxypregn-4-en-3-one
  • Chemical Name: (20R)-20-hydroxypregn-4-en-3-one
  • CAS Number: 145-15-3
  • Molecular Formula: C21H32O2
  • Molecular Weight: 316.47800
  • Create Date: 2018-09-27 21:57:42
  • Modify Date: 2024-01-03 13:55:20

Name (20R)-20-hydroxypregn-4-en-3-one
Synonyms 20beta-Dihydroprogesterone
4-pregnen-20B-ol-3-one
EINECS 205-650-0
4-PREGNEN-20-β-OL-3-ONE
20(R)-Hydroxypregn-4-en-3-one
Density 1.09 g/cm3
Boiling Point 451.7ºC at 760 mmHg
Molecular Formula C21H32O2
Molecular Weight 316.47800
Flash Point 192.4ºC
Exact Mass 316.24000
PSA 37.30000
LogP 4.51530

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5560000
CHEMICAL NAME :
Pregn-4-en-3-one, 20-beta-hydroxy-
CAS REGISTRY NUMBER :
145-15-3
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H32-O2
MOLECULAR WEIGHT :
316.53

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
35 mg/kg
SEX/DURATION :
female 7 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
JEMEAV Journal of Experimental Medicine. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1896- Volume(issue)/page/year: 102,347,1955
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
5 mg/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
ACEDAB Acta Endocrinologica, Supplementum (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) No.1- 1948- Volume(issue)/page/year: 28,18,1956

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Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 100 - 103

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Literature: Journal of Medicinal Chemistry, , vol. 52, # 19 p. 6012 - 6023

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Literature: Journal of the American Chemical Society, , vol. 81, p. 1960,1963

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Literature: Journal of the American Chemical Society, , vol. 73, p. 1528,1530

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Literature: Phytochemistry (Elsevier), , vol. 37, # 3 p. 723 - 726

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Literature: Gazzetta Chimica Italiana, , vol. 85, p. 51,54 Journal of the Chemical Society, , p. 3426,3429

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Detail
Literature: Steroids, , vol. 31, # 3 p. 315 - 325

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Literature: Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 35, # 6 p. 407 - 410

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Detail
Literature: Steroids, , vol. 31, # 3 p. 315 - 325