BioBioPha
China
Product Name: Berberrubine
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Berberrubine
Price: ￥868.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Berberrubine
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Berberrubine chloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

15401-69-1

15401-69-1 structure

15401-69-1 structure

Name: Berberrubine
Chemical Name: berberrubine, hydrochloride, dihydrate
CAS Number: 15401-69-1
Molecular Formula: C₁₉H₁₆ClNO₄
Molecular Weight: 357.788
Catalog: Biochemical Plant extracts
Create Date: 2018-08-27 15:10:53
Modify Date: 2024-01-02 19:31:51
Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model[1].

Name	berberrubine, hydrochloride, dihydrate
Synonyms	berberoline chloride berberrubine 2,3-methylenedioxy-9-hydroxy-10-methoxyprotoberberine chloride Berberrubine chloride 5,6-Dihydro-9-hydroxy-10-methoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride 9-Hydroxy-10-methoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride Beroline chloride berberrubine hydrochloride beberrubine chloride 9-Demethoxy-9-hydroxyberberinium chloride Chileninone hydrochloride berberrubine Berberubine hydrochloride 1,3-Benzodioxolo[5,6-a]benzo[g]quinolizinium, 5,6-dihydro-9-hydroxy-10-methoxy-, chloride (1:1) 9-Berberoline chloride

Description	Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Yu XT, et al. Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice. PLoS One. 2018 Mar 14;13(3):e0194069.

Melting Point	245℃ (DEC.)
Molecular Formula	C₁₉H₁₆ClNO₄
Molecular Weight	357.788
Exact Mass	357.076782
PSA	51.80000
Vapour Pressure	4.28E-15mmHg at 25°C
Index of Refraction	1.724
Storage condition	2-8C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE5399000

CHEMICAL NAME :: Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9-hydroxy-10-methoxy-, chloride

CAS REGISTRY NUMBER :: 15401-69-1

LAST UPDATED :: 199009

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H16-N-O4.Cl

MOLECULAR WEIGHT :: 357.81

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 22,856,1988

633-65-8 structure

633-65-8

~10%

15401-69-1 structure

15401-69-1

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 7 p. 1762 - 1765

108275-17-8 structure

108275-17-8

~92%

15401-69-1 structure

15401-69-1

Literature: Pharmaceutical Chemistry Journal, , vol. 22, # 11 p. 856 - 857 Khimiko-Farmatsevticheskii Zhurnal, , vol. 22, # 11 p. 1348 - 1349

Precursor 2
633-65-8 108275-17-8
DownStream 0