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144978-35-8

144978-35-8 structure
144978-35-8 structure

Name Ethyl Boc-D-Pyroglutamate
Synonyms 2-Ethyl 1-(2-methyl-2-propanyl) (2R)-5-oxo-1,2-pyrrolidinedicarboxylate
1-tert-Butyl 2-ethyl (2R)-5-oxopyrrolidine-1,2-dicarboxylate
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)-
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2R)-
Boc-D-Pyr-OEt
N-Boc-L-pyroglutamic Acid Ethyl Ester
Ethyl N-(tert-Butoxycarbonyl)-D-pyroglutamate
(R)-1-(tert-Butoxycarbonyl)-5-oxopyrrolidine-2-carboxylic Acid Ethyl Ester
N-(tert-Butoxycarbonyl)-D-pyroglutamic Acid Ethyl Ester
1-O-tert-butyl 2-O-ethyl (2R)-5-oxopyrrolidine-1,2-dicarboxylate
N-Boc-D-pyroglutamic Acid Ethyl Ester
Ethyl N-Boc-D-pyroglutamate
1-tert-butyl 2-ethyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate
2-Ethyl 1-(2-methyl-2-propanyl) (2S)-5-oxo-1,2-pyrrolidinedicarboxylate
Ethyl (R)-1-Boc-5-oxopyrrolidine-2-carboxylate
1-Boc-D-Pyroglutamic acid ethyl ester
(R)-1-Boc-5-oxopyrrolidine-2-carboxylic Acid Ethyl Ester
Ethyl (R)-1-(tert-Butoxycarbonyl)-5-oxopyrrolidine-2-carboxylate
Density 1.2±0.1 g/cm3
Boiling Point 375.0±35.0 °C at 760 mmHg
Melting Point 54.0 to 58.0 °C
Molecular Formula C12H19NO5
Molecular Weight 257.283
Flash Point 180.6±25.9 °C
Exact Mass 257.126312
PSA 72.91000
LogP 0.09
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.487
Hazard Codes Xi
HS Code 2933790090

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144978-35-8 structure

144978-35-8

Literature: Bristol-Myers Squibb Company Patent: US2008/9497 A1, 2008 ; Location in patent: Page/Page column 70-71 ; US 20080009497 A1

~58%

144978-35-8 structure

144978-35-8

Literature: EXELIXIS, INC.; IBRAHIM, Mohamed, Abdulkader; JEONG, Joon, Won; JOHNSON, Henry William, Beecroft; KEARNEY, Patrick; LEAHY, James, W.; LEWIS, Gary, L.; NOGUCHI, Robin, Tammie; NUSS, John, M. Patent: WO2010/45580 A1, 2010 ; Location in patent: Page/Page column 87-88 ; WO 2010/045580 A1

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144978-35-8 structure

144978-35-8

Literature: US2002/198255 A1, ; US 20020198255 A1

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144978-35-8 structure

144978-35-8

Literature: Organic and Biomolecular Chemistry, , vol. 4, # 14 p. 2696 - 2709
HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%