422508-46-1

422508-46-1 structure

Name: PU24FCl
Chemical Name: 8-(2-Chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-(4-pentyn-1-yl)-9H -purin-6-amine
CAS Number: 422508-46-1
Molecular Formula: C₂₀H₂₁ClFN₅O₃
Molecular Weight: 433.86400
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2017-03-14 09:13:26
Modify Date: 2025-10-28 18:43:38
PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1].

Name	8-(2-Chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-(4-pentyn-1-yl)-9H -purin-6-amine

Description	PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	HSP90
References	[1]. Vilenchik M, et, al. Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. Chem Biol. 2004 Jun;11(6):787-97.