PU24FCl

Modify Date: 2024-04-09 01:56:35

PU24FCl Structure
PU24FCl structure
Common Name PU24FCl
CAS Number 422508-46-1 Molecular Weight 433.86400
Density N/A Boiling Point N/A
Molecular Formula C20H21ClFN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PU24FCl


PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1].

 Names

Name 8-(2-Chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-(4-pentyn-1-yl)-9H -purin-6-amine

 PU24FCl Biological Activity

Description PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1].
Related Catalog
Target

HSP90

References

[1]. Vilenchik M, et, al. Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. Chem Biol. 2004 Jun;11(6):787-97.  

 Chemical & Physical Properties

Molecular Formula C20H21ClFN5O3
Molecular Weight 433.86400
Exact Mass 433.13200
PSA 97.31000
LogP 3.81220
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