Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Alpha-caryophyllene
Price: ￥1358.0/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Alpha-caryophyllene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU-CHEM CAS NO.6753-98-6 ALPHA-CARYOPHYLLENE
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

6753-98-6

6753-98-6 structure

6753-98-6 structure

Name: Alpha-caryophyllene
Chemical Name: (1E,4E,8E)-α-humulene
CAS Number: 6753-98-6
Molecular Formula: C₁₅H₂₄
Molecular Weight: 204.35100
Catalog: Biochemical Plant extracts
Create Date: 2018-05-22 08:00:00
Modify Date: 2024-01-04 12:56:49
α-Humulene is a main constituent of Tanacetum vulgare L. (Asteraceae) essential oil with anti-inflammation (IC50=15±2 µg/mL). α-Humulene inhibits COX-2 and iNOS expression[1].

Name	(1E,4E,8E)-α-humulene
Synonyms	(1E,4E,8E)-alpha-humulene EINECS 229-816-7 α-Caryophyllene MFCD00042689

Description	α-Humulene is a main constituent of Tanacetum vulgare L. (Asteraceae) essential oil with anti-inflammation (IC50=15±2 µg/mL). α-Humulene inhibits COX-2 and iNOS expression[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2 iNOS
In Vitro	The cytotoxicity of α-Humulene against human lung carcinoma A549, colon adenocarcinoma DLD-1, skin fibroblasts WS1 cell lines is 28±1, 43±3, and 24±3 µg/mL, respetctively[1].
References	[1]. Coté H, et al. Anti-Inflammatory, Antioxidant, Antibiotic, and Cytotoxic Activities of Tanacetum vulgare L. Essential Oil and Its Constituents. Medicines (Basel). 2017 May 25;4(2). pii: E34.

Density	0.889 g/mL at 20 °C(lit.)
Boiling Point	166-168 °C(lit.)
Molecular Formula	C₁₅H₂₄
Molecular Weight	204.35100
Flash Point	90°C
Exact Mass	204.18800
LogP	5.03540
Index of Refraction	n20/D 1.503(lit.)
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ4817500

CHEMICAL NAME :: 1,4,8-Cycloundecatriene, 2,6,6,9-tetramethyl-, (E,E,E)-

CAS REGISTRY NUMBER :: 6753-98-6

BEILSTEIN REFERENCE NO. :: 3240075

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intratracheal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >48 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - pulmonary emboli

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 59,78,1986

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	S26-S36
RIDADR	NA 1993 / PGIII
WGK Germany	3
RTECS	GZ4817500
HS Code	2902199090

HS Code	2902199090
Summary	2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%