16655-82-6

16655-82-6 structure

16655-82-6 structure

Name: 3-Hydroxy Carbofuran
Chemical Name: (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate
CAS Number: 16655-82-6
Molecular Formula: C₁₂H₁₅NO₄
Molecular Weight: 237.25
Catalog: analytical chemistry Standard Pesticides, veterinary drugs and fertilizers
Create Date: 2018-04-15 08:00:00
Modify Date: 2024-01-06 23:54:27
3-Hydroxycarbofuran, a major metabolite of Carbofuran, is a reversible acetylcholinesterase (AChE) inhibitor[1].

Name	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate
Synonyms	methylcarbamic acid 2,2-dimethyl-3-hydroxy-2,3-dihydrobenzofuran-7-yl ester 2,3-dihydro-3-hydroxy-2,2-dimethylbenzofuran-7-yl methylcarbamate Carbamic acid,methyl-,2,3-dihydro-2,2-dimethyl-3-hydroxy-7-benzofuranyl ester Methylcarbamic acid 2,3-dihydro-2,2-dimethyl-3-hydroxy-7-benzofuranyl ester Carbofuran-3-hydroxy solution T56 BOT&J C1 C1 DQ IOVM1 MFCD00143168 3,7-Benzofurandiol, 2,3-dihydro-2,2-dimethyl-, 7-(methylcarbamate) Carbofuran-3-hydroxy 2,3-dihydro-2,2-dimethyl-3-hydroxybenzofuran-7-yl methylcarbamate 3-Hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 3-Hydroxycarbofuran 3-Hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofur-7-yl-methylcarbamat 3-hydroxy-2,3-dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate 2,3-Dihydro-2,2-dimethyl-3,7-benzofurandiol 7-(methylcarbamate)

Description	3-Hydroxycarbofuran, a major metabolite of Carbofuran, is a reversible acetylcholinesterase (AChE) inhibitor[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Duraisamy Kempuraj, et al. Carbofuran pesticide toxicity to the eye. Exp Eye Res. 2023 Feb;227:109355.

Density	1.2±0.1 g/cm3
Boiling Point	344.7±42.0 °C at 760 mmHg
Melting Point	140-148ºC
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25
Flash Point	162.2±27.9 °C
Exact Mass	237.100113
PSA	67.79000
LogP	0.21
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.553
Storage condition	APPROX 4°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FB9500000

CHEMICAL NAME :: Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-3-hydroxy-7-benzofuranyl ester

CAS REGISTRY NUMBER :: 16655-82-6

BEILSTEIN REFERENCE NO. :: 1383873

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H15-N-O4

MOLECULAR WEIGHT :: 237.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 100 mg/L

REFERENCE :: TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 18(1),17,1984

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300
Precautionary Statements	P264-P301 + P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+,Xi,F
Risk Phrases	R28
Safety Phrases	S28
RIDADR	UN 2757
RTECS	FB9500000
Packaging Group	II
Hazard Class	6.1(a)
HS Code	2932999099

16709-30-1 structure

16709-30-1

~34%

16655-82-6 structure

16655-82-6

Literature: Keserue, Gyoergy M.; Balogh, Gyoergy; Czudor, Iren; Karancsi, Tamas; Feher, Andras; Bertok, Bela Journal of Agricultural and Food Chemistry, 1999 , vol. 47, # 2 p. 762 - 769

1563-66-2 structure

1563-66-2

~%

16655-82-6 structure

16655-82-6

Literature: Journal of Agricultural and Food Chemistry, , vol. 47, # 2 p. 762 - 769

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%