83-12-5
83-12-5 structure
- Name: Phenindione
- Chemical Name: phenindione
- CAS Number: 83-12-5
- Molecular Formula: C15H10O2
- Molecular Weight: 222.23900
- Catalog: API Blood system medication Anticoagulant and antiplatelet drugs
- Create Date: 2018-03-19 08:00:00
- Modify Date: 2026-07-16 18:49:57
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Phenindione is an anticoagulant which functions as a Vitamin K antagonist.Target: OthersPhenindione(Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5 [1].
| Name | phenindione |
|---|---|
| Synonyms |
2-phenylindene-1,3-dione
2-PHENYL-1H-INDEN-1,3(2H)-DIONE 1H-Indene-1,3(2H)-dione, 2-phenyl Phenillin PHENINDONE Phenyline Phenylindandione Eridione PHENINDIONE Dineval Hemolidione PHENYLINDIONE Emandione Fenindion 1,3-Indandione, 2-phenyl Dindevan Phenhydren Rectadione heducin Phenindion 2-PHENYL-1,3-INDANEDIONE Indion 1,3-Indandione,2-phenyl Danilone 2-PHENYL-1,3-DIKETOHYDRINDENE Hedulin 1,3(2H)-Indenedione, 2-phenyl 2-phenyl-3-indandione EINECS 201-454-4 2-Phenylindandione Phenylen Fenhydren Cronodione Phenyllin 2-phenylindan-dione Phenylin Phenylindanedione 2-phenyl-1h-indene-3(2h)-dione Danedion 2-Phenyl-1H-indene-1,3(2H)-dione 2-Phenyl-indan-1,3-dione 2-fenyloindandion-1,3 Bindan Indema Danilon AURORA KA-4422 Pindione Emandion 2-PHENYL-1,3-INDANDIONE 1H-Indene-1,3(2H)-dione,2-phenyl Indon phenindione(INN) 2-Phenylindan-1,3-dione Athrombon Diadilan Fenilin Theradione Diophindane MFCD00003782 |
| Description | Phenindione is an anticoagulant which functions as a Vitamin K antagonist.Target: OthersPhenindione(Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5 [1]. |
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| Related Catalog | |
| References |
| Density | 1.343g/cm3 |
|---|---|
| Boiling Point | 243.3 °C (0.3 mmHg) |
| Melting Point | 144-148 °C(lit.) |
| Molecular Formula | C15H10O2 |
| Molecular Weight | 222.23900 |
| Flash Point | 208 °C |
| Exact Mass | 222.06800 |
| PSA | 34.14000 |
| LogP | 2.84940 |
| Index of Refraction | 1.703 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H317 |
| Precautionary Statements | P280-P301 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R25 |
| Safety Phrases | S36/37/39-S45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | NK6125000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2914399090 |
| Precursor 8 | |
|---|---|
| DownStream 10 | |
| HS Code | 2914399090 |
|---|---|
| Summary | 2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |