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19962-37-9

19962-37-9 structure
19962-37-9 structure
  • Name: N-2-Acetylguanine
  • Chemical Name: N-(6-oxo-3,7-dihydropurin-2-yl)acetamide
  • CAS Number: 19962-37-9
  • Molecular Formula: C7H7N5O2
  • Molecular Weight: 193.16300
  • Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
  • Create Date: 2018-07-22 13:27:37
  • Modify Date: 2025-08-24 19:52:23
  • N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1].
Name N-(6-oxo-3,7-dihydropurin-2-yl)acetamide
Synonyms 2-Acetamido-6-hydroxypurine
N2-Acetylguanine
N2-acetylguanidine
N-2-Acetylguanine
MFCD00078201
N-Acetylguanine
2-acetylamino-6-hydroxypurine
2-N-Acetylguanine
EINECS 243-443-7
Description N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1].
Related Catalog
In Vitro N2-Acetylguanine completely disrupt a key Watson–Crick pairing interaction between the ligand and RNA[1]. N2-Acetylguanine (20 µM) promotes transcriptional termination in Bacillus subtilis [1].
References

[1]. Matyjasik MM, et al. High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules. 2020 May 13;25(10):2295.

Density 1.83 g/cm3
Melting Point 260 °C
Molecular Formula C7H7N5O2
Molecular Weight 193.16300
Exact Mass 193.06000
PSA 103.53000
Index of Refraction 1.833
Storage condition Refrigerator
Water Solubility practically insoluble
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S24/25
HS Code 2933990090
917239-36-2 structure

917239-36-2

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19962-37-9 structure

19962-37-9

Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727
917239-37-3 structure

917239-37-3

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19962-37-9 structure

19962-37-9

Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727
917239-35-1 structure

917239-35-1

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19962-37-9 structure

19962-37-9

Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727
112233-74-6 structure

112233-74-6

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19962-37-9 structure

19962-37-9

Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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