80473-92-3
80473-92-3 structure
- Name: 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioic acid
- Chemical Name: 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioic acid
- CAS Number: 80473-92-3
- Molecular Formula: C21H26F2O4S
- Molecular Weight: 412.49100
- Create Date: 2019-01-01 20:44:37
- Modify Date: 2026-08-05 10:07:57
| Name | 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioic acid |
|---|---|
| Synonyms |
Fluticasone Impurity 41 Isomer
Androsta-1,4-diene-17-cbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-Methyl-3-oxo-, (6a,11b,16a,1 (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-cbothioic S-acid (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro- 14,17dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]htadeca-3,6-diene-14-cbothioic S-acid (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-cbothioic acid "6a,9a-Difluoro-11β,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17a-cbothioic Acid" Fluticasone intermediate F2 Axon Fluticasone Thioacid Fluticasone Impurity 41 Androsta-1,4-diene-17-cbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, (6a,11b,16a,17a) Noradrenaline Impurity 45 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17a-cbothioic acid Taletrectinib Impurity8 Androsta-1,4-diene-17- cbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-Methyl-3- oxo-,(6α,11β,16α,17α) Androsta-1,4-diene-17-cbothioic acid, 6,9-difluoro (8S,10S,11S,13S)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-cbothioic S-acid 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-cbothioic acid (6α,11,16α,17α) 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17a-cbothioic Acid (8S,10S,11S,13S)-6,9-difluoro-11,17-dihydroxy-10,13,16-trime 11,17-dihydroxy-16-methyl-3-oxo-,(6α,11β,16α,17α) |
| Density | 1.364g/cm3 |
|---|---|
| Boiling Point | 550.003ºC at 760 mmHg |
| Melting Point | 230-231°C |
| Molecular Formula | C21H26F2O4S |
| Molecular Weight | 412.49100 |
| Flash Point | 286.431ºC |
| Exact Mass | 412.15200 |
| PSA | 109.85000 |
| LogP | 3.16770 |
| Index of Refraction | 1.59 |
| Hazard Codes | Xi |
|---|
|
~92%
80473-92-3 |
| Literature: Zheng, Jin; Lai, Qinglin; Dai, Yiru; Zhao, Qingjie; Shen, Jingshan Organic Preparations and Procedures International, 2008 , vol. 40, # 6 p. 566 - 566 |
|
~%
80473-92-3 |
| Literature: WO2004/52912 A1, ; Page 30-31 ; |
| Precursor 2 | |
|---|---|
| DownStream 3 | |
