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Related CAS#:

26091-79-2

26091-79-2 structure
26091-79-2 structure
  • Name: Byakangelicol
  • Chemical Name: 9-[[(2R)-3,3-dimethyloxiran-2-yl]methoxy]-4-methoxyfuro[3,2-g]chromen-7-one
  • CAS Number: 26091-79-2
  • Molecular Formula: C17H16O6
  • Molecular Weight: 316.305
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-08-07 17:11:08
  • Modify Date: 2024-01-08 11:59:26
  • Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory drug on airway inflammation[1].

Name 9-[[(2R)-3,3-dimethyloxiran-2-yl]methoxy]-4-methoxyfuro[3,2-g]chromen-7-one
Synonyms byakangelicol
7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3,3-dimethyloxiranyl)methoxy)-4-methoxy-, (R)-
9-{[(2R)-3,3-Dimethyl-2-oxiranyl]methoxy}-4-methoxy-7H-furo[3,2-g]chromen-7-one
(R)-9-((3,3-Dimethyl-2-oxiranyl)methoxy)-4-methoxyfuro(3,2-g)chromen-7-one
byakangelikol
7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2R)-3,3-dimethyloxiranyl]methoxy]-4-methoxy-
Description Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory drug on airway inflammation[1].
Related Catalog
Target

COX-2

References

[1]. Lin CH, et al. Byakangelicol, isolated from Angelica dahurica, inhibits both the activity and induction of cyclooxygenase-2 in human pulmonary epithelial cells. J Pharm Pharmacol. 2002 Sep;54(9):1271-8.

Density 1.3±0.1 g/cm3
Boiling Point 503.4±50.0 °C at 760 mmHg
Melting Point 106℃
Molecular Formula C17H16O6
Molecular Weight 316.305
Flash Point 258.3±30.1 °C
Exact Mass 316.094696
PSA 74.34000
LogP 2.05
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.592
Storage condition 2-8C
HS Code 2932999099
Precursor  0

DownStream  1

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%