Byakangelicol

Modify Date: 2024-01-08 11:59:26

Byakangelicol Structure
Byakangelicol structure
Common Name Byakangelicol
CAS Number 26091-79-2 Molecular Weight 316.305
Density 1.3±0.1 g/cm3 Boiling Point 503.4±50.0 °C at 760 mmHg
Molecular Formula C17H16O6 Melting Point 106℃
MSDS N/A Flash Point 258.3±30.1 °C

 Use of Byakangelicol


Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory drug on airway inflammation[1].

 Names

Name 9-[[(2R)-3,3-dimethyloxiran-2-yl]methoxy]-4-methoxyfuro[3,2-g]chromen-7-one
Synonym More Synonyms

 Byakangelicol Biological Activity

Description Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory drug on airway inflammation[1].
Related Catalog
Target

COX-2

References

[1]. Lin CH, et al. Byakangelicol, isolated from Angelica dahurica, inhibits both the activity and induction of cyclooxygenase-2 in human pulmonary epithelial cells. J Pharm Pharmacol. 2002 Sep;54(9):1271-8.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 503.4±50.0 °C at 760 mmHg
Melting Point 106℃
Molecular Formula C17H16O6
Molecular Weight 316.305
Flash Point 258.3±30.1 °C
Exact Mass 316.094696
PSA 74.34000
LogP 2.05
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.592
Storage condition 2-8C

 Safety Information

HS Code 2932999099

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

byakangelicol
7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3,3-dimethyloxiranyl)methoxy)-4-methoxy-, (R)-
9-{[(2R)-3,3-Dimethyl-2-oxiranyl]methoxy}-4-methoxy-7H-furo[3,2-g]chromen-7-one
(R)-9-((3,3-Dimethyl-2-oxiranyl)methoxy)-4-methoxyfuro(3,2-g)chromen-7-one
byakangelikol
7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2R)-3,3-dimethyloxiranyl]methoxy]-4-methoxy-
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