68401-05-8
68401-05-8 structure
- Name: Kuwanon E
- Chemical Name: Kuwanon E
- CAS Number: 68401-05-8
- Molecular Formula: C25H28O6
- Molecular Weight: 424.486
- Catalog: Natural product Flavonoids
- Create Date: 2017-03-26 15:06:40
- Modify Date: 2025-08-23 13:59:24
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Kuwanon E is a flavonoid isolated from Morus alba, cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β[1].
| Name | Kuwanon E |
|---|---|
| Synonyms |
4H-1-Benzopyran-4-one, 2-(5-((2E)-3,7-dimethyl-2,6-octadienyl)-2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2S)-
4H-1-Benzopyran-4-one, 2-[5-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-, (2S)- (2S)-2-{5-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl}-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one |
| Description | Kuwanon E is a flavonoid isolated from Morus alba, cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β[1]. |
|---|---|
| Related Catalog | |
| Target |
Kuwanon E shows cytotoxic activity against THP-1 human monocytic leukemic cell line, with an IC50 of 4.0±0.08 μM[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 678.3±55.0 °C at 760 mmHg |
| Molecular Formula | C25H28O6 |
| Molecular Weight | 424.486 |
| Flash Point | 232.0±25.0 °C |
| Exact Mass | 424.188599 |
| PSA | 107.22000 |
| LogP | 6.60 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.629 |
| Hazard Codes | Xi |
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