68401-05-8

68401-05-8 structure
68401-05-8 structure
  • Name: Kuwanon E
  • Chemical Name: Kuwanon E
  • CAS Number: 68401-05-8
  • Molecular Formula: C25H28O6
  • Molecular Weight: 424.486
  • Catalog: Natural product Flavonoids
  • Create Date: 2017-03-26 15:06:40
  • Modify Date: 2024-01-02 17:23:12
  • Kuwanon E is a flavonoid isolated from Morus alba, cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β[1].

Name Kuwanon E
Synonyms 4H-1-Benzopyran-4-one, 2-(5-((2E)-3,7-dimethyl-2,6-octadienyl)-2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2S)-
4H-1-Benzopyran-4-one, 2-[5-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-, (2S)-
(2S)-2-{5-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl}-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one
Description Kuwanon E is a flavonoid isolated from Morus alba, cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β[1].
Related Catalog
Target

Kuwanon E shows cytotoxic activity against THP-1 human monocytic leukemic cell line, with an IC50 of 4.0±0.08 μM[1].

References

[1]. Zelová H, et al. Evaluation of anti-inflammatory activity of prenylated substances isolated from Morus alba and Morus nigra. J Nat Prod. 2014 Jun 27;77(6):1297-303.

Density 1.3±0.1 g/cm3
Boiling Point 678.3±55.0 °C at 760 mmHg
Molecular Formula C25H28O6
Molecular Weight 424.486
Flash Point 232.0±25.0 °C
Exact Mass 424.188599
PSA 107.22000
LogP 6.60
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.629
Hazard Codes Xi