72795-26-7

72795-26-7 structure

Name: Zenidolol
Chemical Name: erythro-(+/-)-(7-methylindan-4-yloxy)-3-isopropylaminobutan-2-ol
CAS Number: 72795-26-7
Molecular Formula: C₁₇H₂₇NO₂
Molecular Weight: 277.40200
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2017-07-30 17:00:01
Modify Date: 2024-01-07 08:07:36
Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with Ki values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research[1].

Name	erythro-(+/-)-(7-methylindan-4-yloxy)-3-isopropylaminobutan-2-ol
Synonyms	(+/-)-3-isopropylamino-1-(7-methylindan-4-yloxy)butan-2-ol (2R,3R)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol erythro-DL-1-(7-Methylindan-4-yloxy)-3-isopropylaminobutan-2-ol

Description	Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with Ki values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Inflammation/Immunology
References	[1]. Hoffmann C, et al. Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):151-9.