Top Suppliers:I want be here
Related CAS#:
1436000-42-8 79421-76-4
1401559-20-3 1574473-66-7
1270313-51-3 1574327-89-1
1213935-65-9 1574404-05-9
1574473-39-4 1243321-72-3

5289-74-7

5289-74-7 structure
5289-74-7 structure
  • Name: Hydroxyecdysone
  • Chemical Name: 20-hydroxyecdysone
  • CAS Number: 5289-74-7
  • Molecular Formula: C27H44O7
  • Molecular Weight: 480.634
  • Catalog: Biochemical Natural product
  • Create Date: 2018-07-04 18:55:43
  • Modify Date: 2026-07-12 17:12:55
  • Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Cyanotis arachnoides C.B.Clarke which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1].Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2].
Name 20-hydroxyecdysone
Synonyms ECDYSONE, B-(P)
CRUSTECDYSONE
isoinokosterone
β-Ecdysone, Ecdysterone, Insect moulting hormone, Polypodine A, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one
β-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
BETA-ECDYSTERONE
2-beta,3-beta,14,20,22,25-hexahydroxy-5-beta-cholet-7-en-6-one
2BETA,3BETA,14ALPHA,20BETA,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
B-ECDYSONE
b-Ecdysone
2b,3b,14a,20b,22,25-hexahydroxycholest-7-en-6-one
commisterone
BETA-ECDYSONE, UV
BETA-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
20-Hydroxyedysone
Ecdysten
hydroxyecdysone
20-beta-ecdysterone
ecdysteron
Hydroxyecdysterone
Beta Ecdysterone UV, with 20-hydroxyecdysterone
MFCD00036740
Polypodin A
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-TRIHYDROXY-10,13-DIMETHYL-17-((1R,2R)-1,2,5-TRIHYDROXY-1,5-DIMETHYL-HEXYL)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-6-ONE
20-HYDROXYECDYSONE
20-HYDROXYECDYSONE (B-ECDYSTERONE)
(2b,3b,5b,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one
crustecdyson
Viticosterone
crustecdysone
professional manufacturer Ecdysterone 5-7
ECDYSONE, BETA-(RG)(PLEASE CALL)
HYDROXYECDYSONE, 20
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylhtan-2-yl)-1,2,3,4,5,10,11,12,13,15,16,17-dodecahydro-9H-cyclopenta[a]phenanthren-6(14H)-one
the-7
BETA-ECDYSON
2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one
β-ecdysone
2β,3β,14α,20β,22,25-Hexahydroxycholest-7-en-6-one
(2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one
SS-ECDYSONE,2,3,14,20,22,25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
β-Ecdysone, Ecdysterone, Insect moulting hormone
20-Hydroxyecdysone, froM achnoides C. B. Clke
BETA-ECDYSONE, HPLC
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-Trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methyl-2-heptanyl]-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]phenanthren-6-one
20-Hydroxyecdysone, >=
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-diMethyl-17-((2R,3R)-2,3,6-trihydroxy-6-Methylhtan-2-yl)-2,3,4,5,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6(10H)-one
POLYPODINE A
ECDYSTERONE
7,(5B)-CHOLESTEN-2BETA, 3BETA, 14ALPHA, 20BETA, 22R, 25-HEXOL-6-ONE
20-HYDROXYECDYSON
Edysterone
INSECT MOULTING HORMONE
BETA-ECDYSONE
Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2b,3b,5b,22R)
2,3,14,20,22,25-hexahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-Trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methyl-2-heptanyl]-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]phenanthren-6-on
20-Hydroxyecdysone,β-Ecdysone, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one, Ecdysterone, Insect moulting hormone, Polypodine A
B-ecdysone,Commisterone
Isoinokosterone
Commisterone
2B,3B,14A,20,22[R],25-HEXAHYDROXY-7-CHOLESTEN-6-ONE
3-beta,14,20,22,25-hexahydroxy-2-bet(22r)-5-beta-cholest-7-en-6-on
ECDYSONE, BETA
20-Hydroxyecdysone from achnoides C. B. Clke
Ecdysterone
Cyanotis achnoidea Extract (Ecdysone、Beta-ecdysterone)
Description Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Cyanotis arachnoides C.B.Clarke which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1].Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2].
Related Catalog
References

[1]. Liu H, et al. E93 predominantly transduces 20-hydroxyecdysone signaling to induce autophagy and caspase activity in Drosophila fat body. Insect Biochem Mol Biol. 2014 Feb;45:30-9.

[2]. Phungphong S, et al. 20-Hydroxyecdysone attenuates cardiac remodeling in spontaneously hypertensive rats. Steroids. 2017 Oct;126:79-84.
Density 1.3±0.1 g/cm3
Boiling Point 702.1±60.0 °C at 760 mmHg
Melting Point 242-244 °C
Molecular Formula C27H44O7
Molecular Weight 480.634
Flash Point 392.4±29.4 °C
Exact Mass 480.308716
PSA 138.45000
LogP -0.53
Vapour Pressure 0.0±5.0 mmHg at 25°C
Index of Refraction 1.597
Storage condition 2-8°C
Water Solubility alcohol: soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FZ8060000
CHEMICAL NAME :
5-beta-Cholest-7-en-6-one, 2-beta,3-beta,14,20,22,25-hexahydroxy-, (22R)-
CAS REGISTRY NUMBER :
5289-74-7
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C27-H44-O7
MOLECULAR WEIGHT :
480.71
WISWESSER LINE NOTATION :
L E5 B666 LV JUTJ A1 E1 FXQ1&YQ2XQ1&1 IQ OQ PQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>9 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
350 ug/kg
SEX/DURATION :
male 7 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
100 nmol/L
REFERENCE :
ENZYAS Enzymologia. (The Hague, Netherlands) V.1-43, 1936-72. Volume(issue)/page/year: 41,183,1971
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS FZ8060000
Packaging Group II; III
Hazard Class 4.1
HS Code 2937290090
HS Code 2937290090
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:5289-74-7 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 5289-74-7 | Chemsrc address: https://m.chemsrc.com/en/baike/314534.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2026 ChemSrc All Rights Reserved