- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1,5-Dicaffeoylquinic acid
- Price:
- Purity: 89.5%
- Stocking Period: 10 Day
- Contact: Yang
- BioBioPha
- China
- Product Name: Cynarin
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1,5-Dicaffeoylquinic acid
- Price: ￥988.0/20mg ￥1608.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Cynarin
- Price: $600.0/50mg $1000.0/100mg $1900.0/250mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Cynarin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
30964-13-7
30964-13-7 structure
- Name: 1,5-Dicaffeoylquinic acid
- Chemical Name: 1,3-dicaffeoylquinic acid
- CAS Number: 30964-13-7
- Molecular Formula: C25H24O12
- Molecular Weight: 516.451
- Catalog: Biochemical Plant extracts
- Create Date: 2018-09-20 15:22:46
- Modify Date: 2024-01-02 19:46:55
-
Cynarin is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities.
| Name | 1,3-dicaffeoylquinic acid |
|---|---|
| Synonyms |
Listrocol
Acido,1,4-dicaffeilchinico (1R,3R,4S,5R)-1,3-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-4,5-dihydroxycyclohexanecarboxylic acid [1R-(1a,3a,4a,5b)]-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxycyclohexanecarboxylic Acid 1,5-Dicaffeoylquinic acid 1,3-DICAFFEOYLQUINIC ACID 1,3-O-Dicaffeoylquinic acid (1R,3R,4S,5R)-1,3-Bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-4,5-dihydroxycyclohexanecarboxylic acid 1-Carboxy-4,5-dihydroxy-1,3-cyclohexylenebis-(3,4-dihydroxycinnamate) 3,4-Dihydroxycinnamic Acid 1-Carboxy-4,5-dihydroxy-1,3-cyclohexylene Ester CINARINE 1,4-Dicaffeylquinic acid MFCD00075714 Caffeic Acid 1-Carboxy-4,5-dihydroxy-1,3-cyclohexylene Ester Cinarcaf Cyclohexanecarboxylic acid, 1,3-bis[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)- 1,5-Dicaffeylquinic Acid Cynarine Cynara scolymus L, Quinic Acid 1,5-Dicaffeic Ester Plemocil Cynarin CINARAN EINECS 214-655-7 Dicaffeoylquinic Acid, 1,3- |
| Description | Cynarin is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities. |
|---|---|
| Related Catalog | |
| In Vitro | Cynarin inhibits taste receptors, making water to be sweet. It has been shown to have some pharmacological properties including hypocholesterolemic, hepatoprotective, antiviral, antibacterial, and antihistamic effects. Cynarin has marked antioxidant, anticholinergic, reducing ability, radical-scavenging, and metal-binding activities. Cynarin demonstrates 87.72% inhibition of linoleic acid lipid peroxidation at 30 mg/mL concentration. Cynarin exhibits effective DMPD+, ABTS+/sup>, O2-, DPPH1, and H2O2 scavenging effects, reducing capabilities and Fe2+ chelating effects. IC50 and Ki of cynarin for acetylcholinesterase enzyme inhibition are 243.67nM and 39.34±13.88 nM, respectively[1]. Cynarin is a potential immunosuppressant that blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin blocks about 87% of the CD28-dependent "signal 2" pathway of T-cell activation under the condition of one to one ratio of T-cell and B-cell. Cynarin binds to the "G-pocket" of CD28 and thus interrupts the site of interaction between CD28 and CD80[2]. |
| Cell Assay | The cytotoxicity of cynarin treatment of T-cells is measured by MTT colorimetric assay. 100 μL Jurkat cells are incubated with cynarin (0-1000 μg/mL) for 24 h at 37°C. The cell solution is then centrifuged and the supernatant removed. 200 μL of MTT is added and the cell solution is incubated again for 4 h at 37°C. 200 μL of DMSO lysis buffer is added into the cell medium and the concentration of dissolved MTT crystals is measured by plate reader at 560 nm[2]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 819.9±65.0 °C at 760 mmHg |
| Melting Point | 225-227 °C |
| Molecular Formula | C25H24O12 |
| Molecular Weight | 516.451 |
| Flash Point | 278.1±27.8 °C |
| Exact Mass | 516.126770 |
| PSA | 211.28000 |
| LogP | 1.64 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.719 |
| Storage condition | 2-8°C |
| RIDADR | NONH for all modes of transport |
|---|---|
| HS Code | 2932999099 |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |