7460-43-7

7460-43-7 structure

Name: Rubiadin 1-methyl ether
Chemical Name: rubiadin 1-methyl ether
CAS Number: 7460-43-7
Molecular Formula: C₁₆H₁₂O₄
Molecular Weight: 268.264
Catalog: Natural product Anthraquinone
Create Date: 2018-09-27 17:18:46
Modify Date: 2025-08-27 19:49:59
Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].

Name	rubiadin 1-methyl ether
Synonyms	9,10-Anthracenedione, 3-hydroxy-1-methoxy-2-methyl- 9,10-Anthracenedione,3-hydroxy-1-methoxy-2-methyl 3-Hydroxy-1-methoxy-2-methylanthraquinone 1,3-dimethoxy-2-methylanthraquinone 3-Hydroxy-1-methoxy-2-methyl-anthraquinone 3-Hydroxy-1-methoxy-2-methyl-9,10-anthraquinone rubiadin-1-methyl ether 3-Hydroxy-1-methoxy-2-methyl-anthrachinon

Description	Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].
Target	p65
References	[1]. He YQ, et al. Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway. Biochem Biophys Res Commun. 2018 Dec 2;506(4):927-931.

Hazard Codes	Xi
HS Code	2914690090

117-02-2

77-78-1

7460-43-7

Literature: Molecules, , vol. 18, # 8 p. 10042 - 10055

2324-25-6

7460-43-7

Literature: Journal of the Chemical Society, , p. 1699,1707

117-02-2

7460-43-7

Literature: Journal of the Chemical Society [Section] C: Organic, , p. 854 - 857

HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%