669556-37-0
669556-37-0 structure
- Name: THP-PEG8-Tos
- Chemical Name: 17-(tetrahydro-2H-pyran-2-yloxy)-3,6,9,12,15-pentaoxaheptadecyl 4-methylbenzenesulfonate
- CAS Number: 669556-37-0
- Molecular Formula: C24H40O10S
- Molecular Weight: 520.63300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-01-02 14:27:42
- Modify Date: 2025-09-18 12:27:33
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THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 17-(tetrahydro-2H-pyran-2-yloxy)-3,6,9,12,15-pentaoxaheptadecyl 4-methylbenzenesulfonate |
|---|---|
| Synonyms |
17-[(tetrahydro-2H-pyran-2-yl)oxy]-1-tosyloxy-3,6,9,12,15-pentaoxaheptadecane
1-(2H-tetrahydropyran-2-yloxy)-17-tosyloxy-3,6,9,12,15-pentaoxaheptadecane |
| Description | THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C24H40O10S |
|---|---|
| Molecular Weight | 520.63300 |
| Exact Mass | 520.23400 |
| PSA | 116.36000 |
| LogP | 3.40730 |
| Precursor 0 | |
|---|---|
| DownStream 3 | |
