Name | 17-(tetrahydro-2H-pyran-2-yloxy)-3,6,9,12,15-pentaoxaheptadecyl 4-methylbenzenesulfonate |
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Synonyms |
17-[(tetrahydro-2H-pyran-2-yl)oxy]-1-tosyloxy-3,6,9,12,15-pentaoxaheptadecane
1-(2H-tetrahydropyran-2-yloxy)-17-tosyloxy-3,6,9,12,15-pentaoxaheptadecane |
Description | THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C24H40O10S |
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Molecular Weight | 520.63300 |
Exact Mass | 520.23400 |
PSA | 116.36000 |
LogP | 3.40730 |
Precursor 0 | |
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DownStream 3 | |