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868594-48-3

868594-48-3 structure
868594-48-3 structure
  • Name: Benzyl-PEG9-alcohol
  • Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • CAS Number: 868594-48-3
  • Molecular Formula: C25H44O10
  • Molecular Weight: 504.61100
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-05-31 23:56:50
  • Modify Date: 2024-01-15 17:42:41
  • Benzyl-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms Nonaethylene glycol Monobenzyl ether
26-(phenylmethyloxy)-3,6,9,12,15,18,21,24-octaoxahexaeicosan-1-ol
1-Phenyl-2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-ol
Benzyl-PEG9-alcohol
Description Benzyl-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H44O10
Molecular Weight 504.61100
Exact Mass 504.29300
PSA 103.30000
LogP 1.32830
Hazard Codes Xi