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103129-82-4

103129-82-4 structure
103129-82-4 structure
  • Name: Levamlodipine
  • Chemical Name: (S)-Amlodipine
  • CAS Number: 103129-82-4
  • Molecular Formula: C20H25ClN2O5
  • Molecular Weight: 567.051
  • Catalog: API Circulatory system medication Prevention and treatment of angina pectoris
  • Create Date: 2018-04-22 08:00:00
  • Modify Date: 2024-01-02 17:47:28
  • Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].

Name (S)-Amlodipine
Synonyms Norvasc
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-, benzenesulfonate (1:1)
l-Amlodipine
Levamlodipine Besylate Tablets
LevoaMlodipine
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
T6M DHJ B1O2Z CVO2 DR BG& EVO1 F1
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl Ester
Lodien
UNII:1J444QC288
3-Ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Levamlodipine
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methyl (4S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate benzenesulfonate (1:1)
Amlodipine
Levoamlodipine Besylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate
Description Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].
Related Catalog
Target

Calcium channel[1].

References

[1]. Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.

Density 1.2±0.1 g/cm3
Boiling Point 527.2±50.0 °C at 760 mmHg
Melting Point 102-104°C
Molecular Formula C20H25ClN2O5
Molecular Weight 567.051
Flash Point 272.6±30.1 °C
Exact Mass 566.148987
PSA 99.88000
LogP 4.16
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.546
Storage condition -20°C Freezer
Hazard Codes Xi

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103129-82-4 structure

103129-82-4

Literature: WO2008/51056 A1, ; Page/Page column 5; 7; 8 ;

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103129-82-4 structure

103129-82-4

Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702

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103129-82-4 structure

103129-82-4

Literature: Goldmann; Stoltefuss; Born Journal of Medicinal Chemistry, 1992 , vol. 35, # 18 p. 3341 - 3344

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103129-82-4 structure

103129-82-4

Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702

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103129-82-4 structure

103129-82-4

Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702

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103129-82-4 structure

103129-82-4

Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702

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103129-82-4 structure

103129-82-4

Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702

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103129-82-4 structure

103129-82-4

Literature: WO2010/148191 A2, ; Page/Page column 45-49; 59 ;

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103129-82-4 structure

103129-82-4

Literature: Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3341 - 3344
Precursor  2

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