GL Biochem (Shanghai) Ltd.
China
Product Name: H-Ala-Ala-Pro-Val-chloromethylketone
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Nanjing Peptide Biotech Ltd
China
Product Name: H-Ala-Ala-Pro-Val-chloromethylketone
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

90105-47-8

90105-47-8 structure

90105-47-8 structure

Name: H-Ala-Ala-Pro-Val-chloromethylketone hydrochloride salt
Chemical Name: H-Ala-Ala-Pro-Val-chloromethylketone
CAS Number: 90105-47-8
Molecular Formula: C₁₇H₂₉ClN₄O₄
Molecular Weight: 388.89000
Catalog: Signaling Pathways Metabolic Enzyme/Protease Elastase
Create Date: 2019-02-06 23:02:14
Modify Date: 2024-01-10 16:57:07
Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases[1].

Name	H-Ala-Ala-Pro-Val-chloromethylketone
Synonyms	h-ala-ala-pro-val-cmk ala-ala-pro-val-chloromethylketone ala-ala-pro-val-cmk

Description	Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Elastase Research Areas >> Inflammation/Immunology
In Vivo	Methoxysuccinyl-Ala-Ala-Pro-Val chloromethylketone (oropharyngeal aspiration; 85 μM, 40 μL; days 1, 4, and 7) blocks NE-induced cupped cell chemotaxis and significantly reduces Muc5ac gene and protein expression in male Balb/c mice[1].

Molecular Formula	C₁₇H₂₉ClN₄O₄
Molecular Weight	388.89000
Exact Mass	388.18800
PSA	121.60000
LogP	1.19800

21027-01-0 structure

21027-01-0

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

51370-20-8 structure

51370-20-8

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

90105-41-2 structure

90105-41-2

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

90105-46-7 structure

90105-46-7

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

16012-70-7 structure

16012-70-7

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

13485-59-1 structure

13485-59-1

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

63769-98-2 structure

63769-98-2

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

90105-39-8 structure

90105-39-8

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388

61430-05-5 structure

61430-05-5

~%

90105-47-8 structure

90105-47-8

Literature: Martynov, V. F.; Leont'eva, L. I.; Sorochinskaya, E. I.; Smirnov, A. O. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 2 p. 430 - 436,384 - 388