3156-41-0

3156-41-0 structure

Name: Benzene,1-nitro-4-(2-nitroethenyl)-
Chemical Name: β,4-DINITROSTYRENE
CAS Number: 3156-41-0
Molecular Formula: C₈H₆N₂O₄
Molecular Weight: 194.14
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2018-10-17 18:27:48
Modify Date: 2024-01-09 11:05:12
SARS-CoV-2 3CLpro-IN-15 (compound a) is a beta-nitrostyrene coronavirus SARS-CoV-2 inhibitor that targets the SARS-CoV-2 3CL protease (3CLpro). SARS-CoV-2 3CLpro-IN-15 inhibits viral replication and transcription and plays a key role in the discovery of anti-COVID-19 lead compounds[1].

Name	β,4-DINITROSTYRENE
Synonyms	1-(4-nitrophenyl)-2-nitroethene 1-nitro-4-(2-nitrovinyl)benzene ^b,4-Dinitrostyrene 4-Nitro-b-nitrostyrene 1-nitro-2-(4-nitrophenyl)ethene MFCD00052058 4-NITROPHENYLNITROETHENE

Description	SARS-CoV-2 3CLpro-IN-15 (compound a) is a beta-nitrostyrene coronavirus SARS-CoV-2 inhibitor that targets the SARS-CoV-2 3CL protease (3CLpro). SARS-CoV-2 3CLpro-IN-15 inhibits viral replication and transcription and plays a key role in the discovery of anti-COVID-19 lead compounds[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 0.7297 μM (SARS-CoV-2 3CL protease)[1]
References	[1]. Jia ZJ, et al. Synthesis, molecular docking, and binding Gibbs free energy calculation of β-nitrostyrene derivatives: Potential inhibitors of SARS-CoV-2 3CL protease. J Mol Struct. 2023 Jul 15;1284:135409..

HS Code	2904209090
Summary	2904209090 derivatives containing only nitro or only nitroso groups。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%