367927-39-7
367927-39-7 structure
- Name: SMPH Crosslinker
- Chemical Name: N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate
- CAS Number: 367927-39-7
- Molecular Formula: C17H21N3O7
- Molecular Weight: 379.36500
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-10-23 08:28:11
- Modify Date: 2025-08-26 07:50:51
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SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate |
|---|---|
| Synonyms | (2,5-dioxopyrrolidin-1-yl) 6-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]hexanoate |
| Description | SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C17H21N3O7 |
|---|---|
| Molecular Weight | 379.36500 |
| Exact Mass | 379.13800 |
| PSA | 130.16000 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
