55750-62-4
55750-62-4 structure
- Name: N-Succinimidyl 3-maleimidopropionate
- Chemical Name: N-Succinimidyl 3-maleimidopropionate
- CAS Number: 55750-62-4
- Molecular Formula: C11H10N2O6
- Molecular Weight: 266.20700
- Catalog: Chemical reagent Organic reagent Ester Other ester compounds
- Create Date: 2018-06-29 20:45:05
- Modify Date: 2026-07-01 16:34:47
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BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Name | N-Succinimidyl 3-maleimidopropionate |
|---|---|
| Synonyms |
2,5-Dioxo-2,5-dihydro-1H-pyrrole-1-propionic acid 2,5-dioxo-1-pyrrolidinyl ester
N-Succinimidyl3-maleinimidopropionate 3-(Maleimido)propionic acid N-hydroxysuccinimide ester, >= MFCD00043141 3-Maleimidopropionic acid succinimidyl ester 3-Maleimido-propionic NHS este 2,5-Dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl) Succinimidyl 3-maleimidopropionate 3-(2,5-Dioxo-1H-pyrrole-1-yl)propanoic acid succinimidyl ester N-SucciniMidyl 3-(N-MaleiMido)propionate BMPS N-Succinimidyl 3-maleimidopropionate BMPS Crosslinker Mal-beta-Ala-OSu 3-Maleidopropionic acid N-hydroxysuccynimide ester (SMP) 3-MALEIMIDOPROPIONIC ACID N-SUCCINIMIDYL ESTER N-SUCCINIMIDYL3-MALEIMIDOPROPIONATE[CROSS-LINKINEAGENT] N[b-Maleimdopropxyloxy]succinimade ester (2,5-Dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate 3-MaleiMidopropionic acid N-succiniMidyl ester (BMPS) 3-Maleimidopropionic acid NHS N-Succinimidyl 3-maleimido-propanoate 3-(2,5-Dioxo-3-pyrroline-1-yl)propanoic acid succinimidyl ester 1-[3-[(2,5-Dioxopyrrolidin-1-yl)oxy]-3-oxopropyl]-1H-pyrrole-2,5-dione 3-MALEIMIDOPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER MALEIMIDOPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER 3-maleimide propionic acid hydroxysuccinimide ester N-Succinimidyl3-Maleimidopropionate[Cross-linkineagent]> N-(3-MALEIMIDOPROPIONYLOXY)SUCCINIMIDE 3-Maleimidopropionic acid hydroxysuccinimide ester N-β-maleimidopropyl-oxysuccinimide ester 1-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl}-1H-pyrrole-2,5-dione (2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate 3-Maleimidopropionic acid NHS (HPLC) N-Succinimidyl3-Maleimidopropionate，2，5-Dioxo-1-pyrrolidinyl3-(2，5-Dioxo-2，5-dihydro-1-pyrrolyl)propionate N-Maleoyl-β-alanine Nμ-hydroxysuccinimide ester MPS (NHS-3-maleimidopropionate) 2,5-Dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-propanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester 2,5-Dioxo-3-pyrroline-1-propionic acid 2,5-dioxopyrrolidine-1-yl ester N-MALEOYL-BETA-ALANINE N'-HYDROXYSUCCINIMIDE ESTER 3-(Maleimido)propionic acid N-hydroxysuccinimide ester ade 3-Maleimidopropionic Acid N-Succinimidyl Ester N-(3-Maleimidopropionyloxy)succinimide NSM N-SucciniMidyl 3-MaleiMidopropionate NHS-(CH2)2-Mal (BMPS) 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester N-Maleoyl-β-alanine N-hydroxysuccinimide ester N-(3-Maleimidopropionyloxy)succinimide, N-Succinimidyl 3-maleimidopropionate, BMPS, N-Maleoyl-β-alanine Nμ-hydroxysuccinimide ester, N-Maleoyl-β-alanine N-hydroxysuccinimide ester [MAL-SPA] N-Succinimidyl 3-maleimide propionate 3-Maleimido-propionic NHS ester 3-(Maleimido)propionic acid N-succinimidyl ester, BMPS, N-(3-Maleimidopropionyloxy)succinimide, N-Maleoyl-β-alanine Nμ-hydroxysuccinimide ester, N-Succinimidyl 3-maleimidopropionate N-Succinimidyl 3-maleimidopropionate(BMPS) N-SUCCINIMIDYL 3-MALEIMIDOPROPIONATE MaleiMide-(CH2)2-NHS 3-Maleimidopropionic acid-NHS ester 2,5-Dioxo-3-pyrroline-1-propionic acid succinimidyl ester N-(3-Maleimidopropionyloxy)succinimide, N-Maleoyl-β-alanine N′-hydroxysuccinimide ester, N-Maleoyl-β-alanine N-hydroxysuccinimide ester, N-Succinimidyl 3-maleimidopropionate, BMPS Cross-linkineagent B-MALEIMIDOPROPIONIC ACID N-*HYDROXYSUCCINIMIDE ESTE 1-{3-[(2,5-Dioxopyrrolidin-1-yl)oxy]-3-oxopropyl}-1H-pyrrole-2,5-dione |
| Description | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Noncleavable |
| Density | 1.55g/cm3 |
|---|---|
| Boiling Point | 448.8ºC at 760mmHg |
| Melting Point | 168-170 °C(lit.) |
| Molecular Formula | C11H10N2O6 |
| Molecular Weight | 266.20700 |
| Flash Point | 225.2ºC |
| Exact Mass | 266.05400 |
| PSA | 101.06000 |
| Index of Refraction | 1.605 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H335 |
| Precautionary Statements | P261 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R37 |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
|
~80%
55750-62-4 |
| Literature: CYTOS BIOTECHNOLOGY AG; WOOD, Andrew; SMITH, Helen, Kathryn; WILMSHURST, Martin, Philip; VAN, Son Thanh Patent: WO2011/23680 A2, 2011 ; Location in patent: Page/Page column 13-14 ; |
|
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55750-62-4 |
| Literature: Tetrahedron Letters, , vol. 39, # 11 p. 1321 - 1324 |
|
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55750-62-4 |
| Literature: US2012/93840 A1, ; |
|
~66%
55750-62-4 |
| Literature: Paterson, Michael J.; Eggleston, Ian M. Synthetic Communications, 2008 , vol. 38, # 2 p. 303 - 308 |
|
~%
55750-62-4 |
| Literature: Song, Hong Y.; Ngai, Mun H.; Song, Zhen Y.; MacAry, Paul A.; Hobley, Jonathan; Lear, Martin J. Organic and Biomolecular Chemistry, 2009 , vol. 7, # 17 p. 3400 - 3406 |
|
~48%
55750-62-4 |
| Literature: Augustin, Manfred; Mueller, Wolfgang Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798 |
|
~%
55750-62-4 |
| Literature: Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6400 - 6407 |
| Precursor 10 | |
|---|---|
| DownStream 1 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |