91840-27-6

91840-27-6 structure

Name: N-methyl-N-dithiocarboxyglucamine sodium
Chemical Name: mgd sodium salt monohydrate
CAS Number: 91840-27-6
Molecular Formula: C₈H₁₆NNaO₅S₂
Molecular Weight: 293.34
Catalog: Research Areas Others
Create Date: 2017-05-18 03:09:28
Modify Date: 2024-02-06 15:02:38
N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity[1].

Name	mgd sodium salt monohydrate
Synonyms	N-Mgdc N-Methyl-D-glucamin dithiocarbamate N-Methyl-N-dithiocarboxyglucamine sodium Sodium N-methyl-D-glucamine-N-carbodithioate n-methyl-d-glucaminedithiocarbamate Sodium N-methyl-D-glucamine dithiocarbamate D-glucitol-1-yl-methyl-dithiocarbamic acid,sodium salt NorathiolTM

Description	N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity[1].
Related Catalog	Research Areas >> Others
In Vivo	N-methyl-N-dithiocarboxyglucamine (1.1 mM/kg；腹腔注射；单剂量) 可显著诱导 Cd 从粪便排泄。而增加处理次数到每周 7 次后，导致小鼠全身 Cd 负荷减少了 50% 以上[1]。
References	[1]. Gale GR, et al. Effects of sodium N-methyl-N-dithiocarboxyglucamine on cadmium distribution and excretion. Life Sci. 1984 Dec 17;35(25):2571-8.