N-methyl-N-dithiocarboxyglucamine sodium

Modify Date: 2025-09-02 16:02:57

N-methyl-N-dithiocarboxyglucamine sodium Structure
N-methyl-N-dithiocarboxyglucamine sodium structure
Common Name N-methyl-N-dithiocarboxyglucamine sodium
CAS Number 91840-27-6 Molecular Weight 293.34
Density N/A Boiling Point 529.9ºC at 760mmHg
Molecular Formula C8H16NNaO5S2 Melting Point 232-233ºC
MSDS N/A Flash Point 274.3ºC

 Use of N-methyl-N-dithiocarboxyglucamine sodium


N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity[1].

 Names

Name mgd sodium salt monohydrate
Synonym More Synonyms

 N-methyl-N-dithiocarboxyglucamine sodium Biological Activity

Description N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity[1].
Related Catalog
In Vivo N-methyl-N-dithiocarboxyglucamine (1.1 mM/kg;腹腔注射;单剂量) 可显著诱导 Cd 从粪便排泄。而增加处理次数到每周 7 次后,导致小鼠全身 Cd 负荷减少了 50% 以上[1]。
References

[1]. Gale GR, et al. Effects of sodium N-methyl-N-dithiocarboxyglucamine on cadmium distribution and excretion. Life Sci. 1984 Dec 17;35(25):2571-8.  

 Chemical & Physical Properties

Boiling Point 529.9ºC at 760mmHg
Melting Point 232-233ºC
Molecular Formula C8H16NNaO5S2
Molecular Weight 293.34
Flash Point 274.3ºC
Exact Mass 311.04700
PSA 171.01000

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36

 Synonyms

N-Mgdc
N-Methyl-D-glucamin dithiocarbamate
N-Methyl-N-dithiocarboxyglucamine sodium
Sodium N-methyl-D-glucamine-N-carbodithioate
n-methyl-d-glucaminedithiocarbamate
Sodium N-methyl-D-glucamine dithiocarbamate
D-glucitol-1-yl-methyl-dithiocarbamic acid,sodium salt
NorathiolTM
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