DC Chemicals Limited
China
Product Name: Bromopride
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Purity: 98.0%
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Contact: Tony Cao

4093-35-0

4093-35-0 structure

4093-35-0 structure

Name: Bromopride
Chemical Name: 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
CAS Number: 4093-35-0
Molecular Formula: C₁₄H₂₂BrN₃O₂
Molecular Weight: 344.247
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-08-17 18:58:31
Modify Date: 2024-01-03 15:25:41
Bromopride is a dopamine antagonist with prokinetic properties， widely used as an antiemetic.

Name	4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
Synonyms	4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide Artomey Valopride 4-amino-5-bromo-N-(2-diethylaminoethyl)-2-anisamide Viaben 4-amino-5-bromo-N-(2-diethylaminoethyl)-2-methoxybenzamide Viadil Digesan Plamet 4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-o-anisamide Benzamide, 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxy- Bromoprida [INN-Spanish] Bromopridum [INN-Latin] Emepride Bromopride Emoril Bromoprida [Spanish]

Description	Bromopride is a dopamine antagonist with prokinetic properties， widely used as an antiemetic.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease

Density	1.3±0.1 g/cm3
Boiling Point	435.8±45.0 °C at 760 mmHg
Melting Point	148-150ºC
Molecular Formula	C₁₄H₂₂BrN₃O₂
Molecular Weight	344.247
Flash Point	217.3±28.7 °C
Exact Mass	343.089539
PSA	67.59000
LogP	2.67
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.565
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ3280000

CHEMICAL NAME :: o-Anisamide, 4-amino-5-bromo-N-(2-(diethylamino)ethyl)-

CAS REGISTRY NUMBER :: 4093-35-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C14-H22-Br-N3-O2

MOLECULAR WEIGHT :: 344.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 545 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 105 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2520 mg/kg

SEX/DURATION :: lactating female 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral

REFERENCE :: PHBHA4 Physiology and Behavior. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1966- Volume(issue)/page/year: 45,1081,1989

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1320 mg/kg

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: PHBHA4 Physiology and Behavior. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1966- Volume(issue)/page/year: 45,1081,1989

Hazard Codes	Xn: Harmful;
Risk Phrases	20/21/22
Safety Phrases	36
WGK Germany	3
RTECS	BZ3280000
HS Code	2924299090

201230-82-2 structure

201230-82-2

1285695-16-0 structure

1285695-16-0

100-36-7 structure

100-36-7

~%

4093-35-0 structure

4093-35-0

Literature: Journal of the American Chemical Society, , vol. 133, # 15 p. 6061 - 6071

5344-78-5 structure

5344-78-5

~%

4093-35-0 structure

4093-35-0

Literature: Journal of the American Chemical Society, , vol. 133, # 15 p. 6061 - 6071

59557-92-5 structure

59557-92-5

~%

4093-35-0 structure

4093-35-0

Literature: Journal of the American Chemical Society, , vol. 133, # 15 p. 6061 - 6071

96-96-8 structure

96-96-8

~%

4093-35-0 structure

4093-35-0

Literature: Journal of the American Chemical Society, , vol. 133, # 15 p. 6061 - 6071

Precursor 6
201230-82-2 1285695-16-0 100-36-7 5344-78-5
59557-92-5 96-96-8
DownStream 0

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%