Bromopride

Modify Date: 2024-01-03 15:25:41

Bromopride Structure
Bromopride structure
 Common Name Bromopride
CAS Number 4093-35-0 Molecular Weight 344.247
Density 1.3±0.1 g/cm3 Boiling Point 435.8±45.0 °C at 760 mmHg
Molecular Formula C14H22BrN3O2 Melting Point 148-150ºC
MSDS N/A Flash Point 217.3±28.7 °C

 Use of Bromopride


Bromopride is a dopamine antagonist with prokinetic properties， widely used as an antiemetic.

 Names

Name 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
Synonym More Synonyms

 Bromopride Biological Activity

Description Bromopride is a dopamine antagonist with prokinetic properties， widely used as an antiemetic.
Related Catalog

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 435.8±45.0 °C at 760 mmHg
Melting Point 148-150ºC
Molecular Formula C14H22BrN3O2
Molecular Weight 344.247
Flash Point 217.3±28.7 °C
Exact Mass 343.089539
PSA 67.59000
LogP 2.67
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.565
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BZ3280000
CHEMICAL NAME :
o-Anisamide, 4-amino-5-bromo-N-(2-(diethylamino)ethyl)-
CAS REGISTRY NUMBER :
4093-35-0
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C14-H22-Br-N3-O2
MOLECULAR WEIGHT :
344.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
545 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
310 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
2520 mg/kg
SEX/DURATION :
lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
REFERENCE :
PHBHA4 Physiology and Behavior. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1966- Volume(issue)/page/year: 45,1081,1989
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
1320 mg/kg
SEX/DURATION :
female 1-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
PHBHA4 Physiology and Behavior. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1966- Volume(issue)/page/year: 45,1081,1989

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases 20/21/22
Safety Phrases 36
WGK Germany 3
RTECS BZ3280000
HS Code 2924299090

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
Artomey
Valopride
4-amino-5-bromo-N-(2-diethylaminoethyl)-2-anisamide
Viaben
4-amino-5-bromo-N-(2-diethylaminoethyl)-2-methoxybenzamide
Viadil
Digesan
Plamet
4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-o-anisamide
Benzamide, 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxy-
Bromoprida [INN-Spanish]
Bromopridum [INN-Latin]
Emepride
Bromopride
Emoril
Bromoprida [Spanish]
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