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112-05-0

112-05-0 structure
112-05-0 structure
  • Name: Nonanoic acid
  • Chemical Name: pelargonic acid
  • CAS Number: 112-05-0
  • Molecular Formula: C9H18O2
  • Molecular Weight: 158.23800
  • Catalog: Organic raw materials Carboxylic compounds and derivatives Acyclic carboxylic acid
  • Create Date: 2018-08-13 14:16:24
  • Modify Date: 2024-01-02 11:29:29
  • Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

Name pelargonic acid
Synonyms nonanic acid
n-Nonanoic acid
NONANOIC-D4 ACID
NONANOIC ACID FOR SYNTHESIS
Nonanoic acid
nonyloic acid
Nona-N-methyl-4,4',4''-methantriyl-tri-anilinium,Tris-jodid
NONANOIC ACID/PELARGONIC ACID
NONANOICACID(PELARGONICACID)
nona-N-methyl-4,4',4''-methanetriyl-tri-anilinium,tris iodide
Nonanoic acid (Pelargonic acid)
noncarboxylic acid
N-NONYLIC ACID
NONANOIC ACID (PELARGONIC)
Acid C9,Pelargonic acid
Pelargonic Acid
MFCD00004433
Nonoic acid
EINECS 203-931-2
NO0NOIC ACID
Description Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].
Related Catalog
In Vitro Nonanoic acid upregulates endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition[1].
References

[1]. Wang J, et al. Caprylic acid and nonanoic acid upregulate endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition.Int Immunopharmacol. 2018 Dec;65:303-311.

Density 0.906 g/mL at 25 °C(lit.)
Boiling Point 268-269 °C(lit.)
Melting Point 9 °C(lit.)
Molecular Formula C9H18O2
Molecular Weight 158.23800
Flash Point 212 °F
Exact Mass 158.13100
PSA 37.30000
LogP 2.82160
Vapour density 5.5 (vs air)
Vapour Pressure <0.1 mm Hg ( 20 °C)
Index of Refraction n20/D 1.432(lit.)
Storage condition 2-8°C
Water Solubility NEGLIGIBLE
Name: n-Nonanoic acid 97% Material Safety Data Sheet
Synonym: Pelargonic Acid
CAS: 112-05-0
Section 1 - Chemical Product MSDS Name:n-Nonanoic acid 97% Material Safety Data Sheet
Synonym:Pelargonic Acid

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
112-05-0 n-Nonanoic acid 97% 203-931-2
Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.
Potential Health Effects
Eye:
Causes eye burns. Causes redness and pain.
Skin:
Causes skin burns. Causes redness and pain.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Chronic exposure may cause effects similar to those of acute exposure.

Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 112-05-0: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Clear liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 254 deg C
Freezing/Melting Point: 12.5 deg C
Autoignition Temperature: Not available.
Flash Point: 114 deg C ( 237.20 deg F)
Explosion Limits, lower: 1.20
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 0.3g/l
Specific Gravity/Density: 0.900
Molecular Formula: C9H18O2
Molecular Weight: 158.1248

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not currently available.
Conditions to Avoid:
None reported.
Incompatibilities with Other Materials:
Bases, oxidizing agents, reducing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 112-05-0: RA6650000 LD50/LC50:
CAS# 112-05-0: Draize test, rabbit, eye: 91 mg Severe; Draize test, rabbit, eye: 100 uL Mild; Draize test, rabbit, skin: 500 mg/24H Moderate; Oral, mouse: LD50 = >5 gm/kg; Oral, rat: LD50 = >5 gm/kg; Skin, rat: LD50 = >2 gm/kg.
Carcinogenicity:
n-Nonanoic acid - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Pseudomonas putida:

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.*
Hazard Class: 8
UN Number: 3265
Packing Group: III
IMO
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 112-05-0: No information available.
Canada
CAS# 112-05-0 is listed on Canada's DSL List.
CAS# 112-05-0 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 112-05-0 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RA6650000
CHEMICAL NAME :
Nonanoic acid
CAS REGISTRY NUMBER :
112-05-0
BEILSTEIN REFERENCE NO. :
1752351
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C9-H18-O2
MOLECULAR WEIGHT :
158.27
WISWESSER LINE NOTATION :
QV8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,839,1978
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
EMERY* Emery Industries, Inc., Data Sheets. (4900 Este Ave., Cincinnati, OH 45232) Volume(issue)/page/year: S3B,-,1964
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,839,1978 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
224 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 18,141,1961 *** REVIEWS *** TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83209 No. of Facilities: 960 (estimated) No. of Industries: 9 No. of Occupations: 16 No. of Employees: 7870 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83209 No. of Facilities: 2266 (estimated) No. of Industries: 49 No. of Occupations: 46 No. of Employees: 76346 (estimated) No. of Female Employees: 6777 (estimated)
Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S28-S36/37/39-S45-S28A
RIDADR UN 3265 8/PG 3
WGK Germany 1
RTECS RA6650000
Packaging Group III
Hazard Class 8
HS Code 2915900090
HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%