| Name | dibutyl phthalate |
|---|---|
| Synonyms |
Dibutyl ester of 1,2-benzenedicboxylic acid
EINECS 201-557-4 1,2-dibutyl 1,2-benzenedicarboxylate Dibutyl phthalate Butylester of dibutylphosphinic acid Genoplast B Di-n-butyl phthalate [-2] caswellno292 NLA-10 DI-N-BUTYL PHTHALATE, 5000MG, NEAT DIBUTYL PHTHALATE PESTANAL ALDITE RESIN DBP n-dibutylphthalate Dibutyl Phthalate benzene-o-dicboxylicaciddi-n-butylester Dibutylphosphinsaeure-butylester Phosphinic acid,dibutyl-,butyl ester dibutylphosphonic acid butyl ester genoplastb n-dibutyl MFCD00282537 Elaol ersoplastfda di-n-butylphthalate(dnbp) ergoplastfdb apesticidechemicalcode028001 ai-3-00283 butyl dibutylphosphinate PHTHALIC ACID, BIS-BUTYL ESTER PHTHALIC ACID DIBUTYL ESTER hexaplasm/b Celluflex DPB Dibutyl o-phthalate hatcoldbp DibutylPhthalate,Certified phthalic acid dibutyl ester dibutyl benzene-1,2-dicarboxylate DibutylPhthalateForSynthesis Dibutyl1,2-benzenedicboxlate Morflex Dibutyl phthalate [-2] phthalic acid di-n-butyl ester DI-N-BUTYLPHTHALATE,M, NEAT dbp(ester) Hexaplas M/B kodaflexdbp dibutylphthalate(1,2-benzenedicboxylacid,dibutylester) di-n-butyl phthalate di-n-butylesterkyselinyftalove 2,6-di-t-butyl-4-methyl-phenol butyl phthalate Benzene-o-dicboxylic acid, di-n-butyl ester N-BUTYL PHTHALATE PHTHALIC ACID DI-N-BUTYL ESTER Kodaflex DBP Di-n-butylphthalate di-n-butyl phthalate solution Benzene-1,2-dicboxylic acid di-n-butylester DIBUTYL PHTHALATE, DIBUTYL PHTHALATE, REAGENTPLUS, >= Palatinol DBP O-BENZENEDICBOXYLIC ACID DIBUTYL ESTER Dibutyll phthalate benzene-1,2-dicboxylicaciddibutylester Dibutylphthalat Palatinol C Bufa di-1-butylphthalate Dibutylphthalate Dibutyl phthalte celluflexdpb Di-n-butyl DI-N-BUTYL PHTHALATE, 1X1ML, MEOH, 5000U G/ML dibutyl-o-phthalate dibutyl-phosphinic acid butyl ester |
| Description | Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications[1]. May cause toxicity and adverse neurobehavioral effects[2][3]. |
|---|---|
| Related Catalog | |
| In Vitro | Dibutyl phthalate (0.001 µg/mL-1000 µg/mL) is detrimental to follicle growth and viability and results in significant dysregulation of cell cycle and apoptosis gene expression in a dose-specific manner. But MBP does not play a role in Dibutyl phthalate toxicity in follicles exposed in vitro[1]. |
| In Vivo | Dibutyl phthalate (200, 400, or 600 mg/kg/day) induces decrease mice weight, impairment of spermatogenesis, reduces serum follicle stimulating hormone and testosterone level, alters testicular LDH, increases LPO, and decreases the levels of enzymatic antioxidants with histopathological anomalies[2]. Dibutyl phthalate (6.25, 12.5, 25, 50, 100 and 200 mg/kg) could cause some neurobehavioral adverse effects in mice[3]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 337.0±10.0 °C at 760 mmHg |
| Melting Point | -35 °C |
| Molecular Formula | C16H22O4 |
| Molecular Weight | 278.344 |
| Flash Point | 171.1±0.0 °C |
| Exact Mass | 278.151794 |
| PSA | 52.60000 |
| LogP | 4.82 |
| Vapour density | 9.6 (vs air) |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.499 |
| Water Solubility | Slightly soluble. 0.0013 g/100 mL |
| Freezing Point | -35℃ |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
| Symbol |
GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360Df-H400 |
| Precautionary Statements | P201-P273-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T:Toxic |
| Risk Phrases | R61;R50;R62 |
| Safety Phrases | S53-S45-S61-S36/37-S16 |
| RIDADR | UN 3082 9/PG 3 |
| WGK Germany | 2 |
| RTECS | TI0875000 |
| Packaging Group | III |
| Hazard Class | 9 |
| HS Code | 2917341090 |
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~96%
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| Literature: Dawar, Pankaj; Raju, M. Bagavan; Ramakrishna, Ramesha Andagar Synthetic Communications, 2014 , vol. 44, # 6 p. 836 - 846 |
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| Literature: McNulty, James; Nair, Jerald J.; Cheekoori, Sreedhar; Larichev, Vladimir; Capretta, Alfredo; Robertson Chemistry - A European Journal, 2006 , vol. 12, # 36 p. 9314 - 9322 |
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| Literature: Applied Catalysis A: General, , vol. 467, p. 430 - 438 |
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| Literature: Hosangadi, Bhaskar D.; Dave, Rajesh H. Tetrahedron Letters, 1996 , vol. 37, # 35 p. 6375 - 6378 |
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| Literature: Applied Catalysis A: General, , vol. 467, p. 430 - 438 |
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| Literature: Collection of Czechoslovak Chemical Communications, , vol. 49, # 1 p. 253 - 266 |
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| Literature: Archiv der Pharmazie (Weinheim, Germany), , vol. 287, p. 457 |
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| Literature: Journal of the Chinese Chemical Society (Peking), , vol. 15, p. 204 |
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| Literature: Applied Catalysis A: General, , vol. 455, p. 183 - 192 |
| Precursor 9 | |
|---|---|
| DownStream 10 | |
| HS Code | 2917349000 |
|---|---|
| Summary | 2917349000 other esters of orthophthalic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |