88-99-3

88-99-3 structure

Name: Phthalic acid
Chemical Name: phthalic acid
CAS Number: 88-99-3
Molecular Formula: C₈H₆O₄
Molecular Weight: 166.131
Catalog: Chemical reagent Organic reagent Aromatic acid
Create Date: 2018-02-13 08:00:00
Modify Date: 2026-06-30 18:28:20
Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers[1].

Name	phthalic acid
Synonyms	o-Dicarboxybenzene 1,2-Benzenedicarboxylic acid QVR BVQ O-DICBOXYBENZENE Phthalic acid Vetec(TM) ade PHTHALIC ACID, PHTHALIC ACID, PHTHALIC ACID, PHTHALIC ACID Acide phtalique 1,2-Benzenedicboxylic acid, Phthalic acid Sunftal 20 o-benzenedicboxylicacid kyselinaftalova 1,2-PHENYL DICBOXYLIC ACID PHTHALIC ACID A.C.S Phthalic acid ade PhthalicAcidForSynthesis 1,2-Benzenedicarboxylate, dihydrogen salt PATHALIC ACID Phthalic acid . p.a., >= (T) 1,2-BENZENEDICBOXYLIC ACID acidhtalique(french) Kyselina ftalova PHTHALIC ACID, 1000MG, NEAT O-PHTHALIC ACID (PHTHALIC ACID ) Phthalsure o-Cboxybenzoic Acid 1,2-phthalicacid Phthalate Ion Chromatoaphy Standd Solution Fluka o-Benzenedicboxylic acid Phthalic acid, For analysis PHTHALIC ACID RECHEM AL BO 0013 acidhtalique Dihydrogen benzene-1,2-dicarboxylate 1,2-BENZENEDICBONXYLIC ACID TOTALBLOT+ PVDF MEMBRANES THALIC ACID 1,2-BENZENEDICABOXYLIC ACID ORTHO-PHTHALICACIDANDITSSODIUMANDPOTASSIUMSALTS Hydrogen phthalate Phthalic acid min Butyphthalide impurity 23 DIISONOYL PHTHALATE (DINP) ortho-phthalic acid 1,2-BENZENEDICBONIC ACID, ANHYDRIDE MFCD00002467 Phthalate standd for IC PhthalicAcid 1,2-dicboxybenzene AURORA o-Phthalic acid ORTHO-PHTHALIC ACID Phthalic acid , >= O-PHTHALIC ACID EINECS 201-873-2 BENZENE-1,2-DICBOXYLIC ACID BENZENE-1,2-DICBOXYLIC ACID / O-PHTHALIC ACID PHTHALATE ION CHROMATOAPHY STANDD 0-Phthalic acid

Description	Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: metabolite of PAEs[1]
References	[1]. Du Yeon Bang, et al.Toxicological Characterization of Phthalic Acid. Toxicol Res 2011;27:191−203

Density	1.5±0.1 g/cm3
Boiling Point	378.3±25.0 °C at 760 mmHg
Melting Point	210-211 °C (dec.)(lit.)
Molecular Formula	C₈H₆O₄
Molecular Weight	166.131
Flash Point	196.7±19.7 °C
Exact Mass	166.026611
PSA	74.60000
LogP	0.81
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.618
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	7 g/L (25 ºC)

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 32(8),12,1967

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,711,1992

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 49,471,1942 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 32(8),12,1967 *** REVIEWS *** TOXICOLOGY REVIEW BPCT** Progress Report from the Environmental Protection Agency to NIOSH on Benzenepolycarboxylates, 1974 Volume(issue)/page/year: -,183,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 59185 No. of Facilities: 106 (estimated) No. of Industries: 4 No. of Occupations: 8 No. of Employees: 2321 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 59185 No. of Facilities: 1480 (estimated) No. of Industries: 22 No. of Occupations: 27 No. of Employees: 19693 (estimated) No. of Female Employees: 2861 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	TH9625000
HS Code	2917399090

HS Code	2916399090
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%