142846-71-7

142846-71-7 structure

Name: M35
Chemical Name: M35 Peptide
CAS Number: 142846-71-7
Molecular Formula: C₁₀₇H₁₅₃N₂₇O₂₆
Molecular Weight: 2233.60
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2018-12-09 07:07:12
Modify Date: 2026-07-08 17:58:42
Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2].

Name	M35 Peptide
Synonyms	GALANIN FRAGMENT -BRADYKININ*FRAGMENT AM H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-G-NH2 Galanin -Bradykinin , amide, M35 GALANIN -BRADYKININ AMIDE Galanin-(1-13)-bradykinin-(2-9)-amide GWTLNSAGYLLGPPPGFSPFR-NH2 GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-G-NH2 L-gininamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-aspaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl M 35 Galanin rectorligand M35 GWTLNSAGYLLGPPPGFSPFR-CONH2 L-Argininamide,glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl

Description	Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	Ki: 0.11 nM (GalR1), 2.0 nM (GalR2)[2]
References	[1]. Kask K, et al. Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59(3):341-8. [2]. Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne). 2012 Dec 7;3:146.

Safety Phrases	22-24/25