M35
Modify Date: 2025-08-25 12:13:13
M35 structure
|
Common Name | M35 | ||
|---|---|---|---|---|
| CAS Number | 142846-71-7 | Molecular Weight | 2233.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C107H153N27O26 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of M35Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2]. |
| Name | M35 Peptide |
|---|---|
| Synonym | More Synonyms |
| Description | Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 0.11 nM (GalR1), 2.0 nM (GalR2)[2] |
| References |
[2]. Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne). 2012 Dec 7;3:146. |
| Molecular Formula | C107H153N27O26 |
|---|---|
| Molecular Weight | 2233.60 |
| Exact Mass | 2232.15000 |
| PSA | 817.65000 |
| LogP | 2.16320 |
| InChIKey | JWMXJVFGTXYBFM-UHFFFAOYSA-N |
| SMILES | CC(C)CC(NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CN)C(C)O)C(=O)NCC(=O)N1CCCC1C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(N)=O |
| Safety Phrases | 22-24/25 |
|---|
| GWTLNSAGYLLGPPPGFSPFR-CONH2 |
| L-Argininamide,glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl |
| M 35 |
| Galanin-(1-13)-bradykinin-(2-9)-amide |