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17328-16-4

17328-16-4 structure
17328-16-4 structure
  • Name: TC-E 5003
  • Chemical Name: 2-chloro-N-[4-[4-[(2-chloroacetyl)amino]phenyl]sulfonylphenyl]acetamide
  • CAS Number: 17328-16-4
  • Molecular Formula: C16H14Cl2N2O4S
  • Molecular Weight: 401.26400
  • Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
  • Create Date: 2016-02-22 14:44:08
  • Modify Date: 2024-01-02 18:27:44
  • TC-E 5003 is a selective PRMT1 inhibitor with an IC50 of 1.5 µM against hPRMT1. TC-E 5003 has anti-inflammatory properties in TLR4 signaling[1][2].

Name 2-chloro-N-[4-[4-[(2-chloroacetyl)amino]phenyl]sulfonylphenyl]acetamide
Synonyms 4',4''-sulfonylbis(2-chloroacetanilide)
Density 1.504g/cm3
Boiling Point 704.2ºC at 760 mmHg
Molecular Formula C16H14Cl2N2O4S
Molecular Weight 401.26400
Flash Point 379.7ºC
Exact Mass 400.00500
PSA 100.72000
LogP 4.10080
Vapour Pressure 1.12E-19mmHg at 25°C
Index of Refraction 1.639

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WR3150000
CHEMICAL NAME :
Sulfone, bis((4-chloroacetylamino)phenyl)
CAS REGISTRY NUMBER :
17328-16-4
BEILSTEIN REFERENCE NO. :
2180613
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H14-Cl2-N2-O4-S
MOLECULAR WEIGHT :
401.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXPAAA Experimental Parasitology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 20,88,1967
HS Code 2924299090
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%