6637-10-1

6637-10-1 structure
6637-10-1 structure
  • Name: 2,3'-Bi-1H-indole,2,3-dihydro-
  • Chemical Name: 3-[(2R)-2,3-dihydro-1H-indol-2-yl]-1H-indole
  • CAS Number: 6637-10-1
  • Molecular Formula: C16H14N2
  • Molecular Weight: 234.30
  • Catalog: Research Areas Cancer
  • Create Date: 2017-10-23 11:19:44
  • Modify Date: 2024-01-10 09:48:35
  • VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].

Name 3-[(2R)-2,3-dihydro-1H-indol-2-yl]-1H-indole
Synonyms 2,3-dihydro-1H,1'H-[2,3']biindolyl
3-(indolin-2-yl)indole
2,3-dihydro-(1,4)dioxino(2,3-c)pyridin-7-carbaldehyde
2-(3-indolyl)-2,3-dihydroindole
2H,3H-[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde
2,3-Dihydro-<2,3'-biindole>
3-(indolin-2-yl)-1H-indole
2-(3'-indolyl)indoline
2-(indol-3-yl)-2,3-dihydroindole
2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxaldehyde
2,3-dihydro[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde
Description VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].
Related Catalog
Target

IC50: 0.31 µM (AR BF3)[1]

References

[1]. Ravi Shashi Nayana Munuganti, et al. Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer. Cancer Res (2014) 74 (19_Supplement): 2508.

Density 1.225g/cm3
Boiling Point 449.3ºC at 760 mmHg
Molecular Formula C16H14N2
Molecular Weight 234.30
Flash Point 225.5ºC
Exact Mass 234.11600
PSA 27.82000
LogP 4.01520
Index of Refraction 1.699