2,3'-Bi-1H-indole,2,3-dihydro-

Modify Date: 2025-08-27 09:07:30

2,3'-Bi-1H-indole,2,3-dihydro- Structure
2,3'-Bi-1H-indole,2,3-dihydro- structure
Common Name 2,3'-Bi-1H-indole,2,3-dihydro-
CAS Number 6637-10-1 Molecular Weight 234.30
Density 1.225g/cm3 Boiling Point 449.3ºC at 760 mmHg
Molecular Formula C16H14N2 Melting Point N/A
MSDS N/A Flash Point 225.5ºC

 Use of 2,3'-Bi-1H-indole,2,3-dihydro-


VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].

 Names

Name 3-[(2R)-2,3-dihydro-1H-indol-2-yl]-1H-indole
Synonym More Synonyms

 2,3'-Bi-1H-indole,2,3-dihydro- Biological Activity

Description VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].
Related Catalog
Target

IC50: 0.31 µM (AR BF3)[1]

References

[1]. Ravi Shashi Nayana Munuganti, et al. Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer. Cancer Res (2014) 74 (19_Supplement): 2508.

 Chemical & Physical Properties

Density 1.225g/cm3
Boiling Point 449.3ºC at 760 mmHg
Molecular Formula C16H14N2
Molecular Weight 234.30
Flash Point 225.5ºC
Exact Mass 234.11600
PSA 27.82000
LogP 4.01520
Index of Refraction 1.699
InChIKey OGXXVLOAJZDVFY-UHFFFAOYSA-N
SMILES c1ccc2c(c1)CC(c1c[nH]c3ccccc13)N2

 Synthetic Route

 Synonyms

2,3-dihydro-1H,1'H-[2,3']biindolyl
3-(indolin-2-yl)indole
2,3-dihydro-(1,4)dioxino(2,3-c)pyridin-7-carbaldehyde
2-(3-indolyl)-2,3-dihydroindole
2H,3H-[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde
2,3-Dihydro-<2,3'-biindole>
3-(indolin-2-yl)-1H-indole
2-(3'-indolyl)indoline
2-(indol-3-yl)-2,3-dihydroindole
2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxaldehyde
2,3-dihydro[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde
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