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90-15-3

90-15-3 structure
90-15-3 structure
Name 1-naphthol
Synonyms ALPHA-NAPHTHOL
c.i.oxidationbase33
Ursol ERN
1-Naphthol
ALPHA-NAPTHOL
a-Naphthol
1-napthol(alpha-napthol)
ALPHA-HYDROXYNAPHTHALENE
ALPHA NAPHTHOL ( INDUSTRIAL ADE )
1-NAPHTHOL
Fourrine 99
1-hydroxynaphthalene
1-naphtol
1-Naphthol, Purified
MFCD00003930
1-NAPHTHOL (ALPHA), FOR FLUORESCENCE
naphthalen-1-ol
1-NAPHTHOL, REAGENTPLUS TM, >=
1-NAPHTHOL FOR ANALYTICAL PURPOSE
BETA NAPHTHAL
cioxidationbase33
1-NAPHTHOL (ALPHA), FOR ANALYTICAL PURPO SES
ALPHA NAPHTHOL ( HIGH ADE )
Molisch's reagent
1-naphthol (alpha)
1-Naphthol-(A-Naphthol)
1-NAPHTHOL R. G., REAG. PH. EUR
NAPHTHOL-1
á-Naphthol
Duloxetine IMpurity D
EINECS 201-969-4
1-NaphtholA.R
α-Maphthol
furro er
1-NAPHTHOL SIGMAULTRA
1-HYDROXYNAPTHALENE
[14C]-1-Naphthol
BETA NAPTHOL MIN
1-NAPHTHOL MM(CRM STANDD)
1-NAPHTHOL PESTANAL
alpha-naphtol
Fourrine ERN
C.I
à-naphthol
durafur developer d
1-napthol(alpha-napthol) industrial ade
Basf Ursol ERN
1-Naphthol 0.5
2-NAPHTHOL
nakotrb
basfursolern
Fouramine ERN
L66J BQ
Zoba ERN
fouramineern
1-HYDROXYNAPHTHALENE
ALPHA NAPHTHO
Oxidation base 33
α-Naphthol
1-naphthalenol
C.I. Oxidation Base 33
α-Hydroxynaphthalene
Description 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Swain J, et al. 1-Naphthol as an ESPT fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media. Phys Chem Chem Phys. 2015 Jul 14;17(26):16752-9.
Density 1.2±0.1 g/cm3
Boiling Point 288.0±0.0 °C at 760 mmHg
Melting Point 94-98ºC
Molecular Formula C10H8O
Molecular Weight 144.170
Flash Point 144.0±10.6 °C
Exact Mass 144.057510
PSA 20.23000
LogP 2.71
Vapour density 4.5 (120 °C, vs air)
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.678
Storage condition Store in dark!
Stability Stable, but air and light sensitive - store under inert gas. Incompatible with strong bases, strong oxidizing agents.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL2800000
CHEMICAL NAME :
1-Naphthol
CAS REGISTRY NUMBER :
90-15-3
LAST UPDATED :
199710
DATA ITEMS CITED :
27
MOLECULAR FORMULA :
C10-H8-O
MOLECULAR WEIGHT :
144.18
WISWESSER LINE NOTATION :
L66J BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1870 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>420 mg/m3/1H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
134 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
9 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
880 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
9100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10920 mg/kg/28D-C
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - urine volume increased
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg/2W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - urine volume increased Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
90 mg/kg
SEX/DURATION :
female 6-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
5 gm/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,19,1977 *** REVIEWS *** TOXICOLOGY REVIEW MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 47,75,1978 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81692 No. of Facilities: 1281 (estimated) No. of Industries: 20 No. of Occupations: 28 No. of Employees: 12938 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81692 No. of Facilities: 5497 (estimated) No. of Industries: 7 No. of Occupations: 24 No. of Employees: 57255 (estimated) No. of Female Employees: 43248 (estimated)
Symbol GHS05 GHS06 GHS09
GHS05, GHS06, GHS09
Signal Word Danger
Hazard Statements H302-H311-H315-H318-H335-H411
Precautionary Statements P273-P280-P302 + P352 + P312-P305 + P351 + P338 + P310-P391
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R21/22;R37/38;R41
Safety Phrases S2-S22-S26-S37/39
RIDADR UN 1759
WGK Germany 1
RTECS QL2800000
Packaging Group III
Hazard Class 6.1
HS Code 2907151000
HS Code 2907151000
Summary HS:2907151000 naphthalen-2-ol VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
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