1055412-47-9
1055412-47-9 structure
- Name: SU 5614
- Chemical Name: 5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2 H-indol-2-one
- CAS Number: 1055412-47-9
- Molecular Formula: C15H13ClN2O
- Molecular Weight: 272.73000
- Create Date: 2017-03-17 18:31:28
- Modify Date: 2024-01-10 10:24:08
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(Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3[1].
| Name | 5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2 H-indol-2-one |
|---|---|
| Synonyms |
5-Chloro-3-[(3,5-dimethylpyrrol-2-yl)methylene]-2-indolinone
1H-Indole-2-carboxylic acid,5-chloro-3-[(3,5-dimethylphenyl)sulfonyl] 5-chloro-3-(3,5-dimethylphenyl-sulfonyl)indole-2-carboxylic acid 5-chloro-3-(3,5-dimethyl-1H-pyrrol-2-yl-methylene)-1,3-dihydro-indol-2-one 5-chloro-3-[(3,5-dimethylphenyl)sulfonyl]-1H-indole-2-carboxylic acid 3-[(3,5-dimethylphenyl)sulfonyl]-1H-indole-2-carboxylic acid SU 5614 SU5614 |
| Description | (Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C15H13ClN2O |
|---|---|
| Molecular Weight | 272.73000 |
| Exact Mass | 272.07200 |
| PSA | 48.38000 |
| LogP | 3.86270 |
| Hazard Statements | H413 |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |