141184-34-1

141184-34-1 structure

Name: Filaminast
Chemical Name: [(E)-1-(3-cyclopentyloxy-4-methoxyphenyl)ethylideneamino] carbamate
CAS Number: 141184-34-1
Molecular Formula: C₁₅H₂₀N₂O₄
Molecular Weight: 292.33000
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2017-12-27 03:13:19
Modify Date: 2024-03-01 12:00:53
WAY-PDA 641 is a potent and preferential PDE-IV inhibitor, with an IC50 of 0.42 μM for canine trachealis PDE-IV. WAY-PDA 641 induces respiratory muscle relaxation and bronchodilation[1].

Name	[(E)-1-(3-cyclopentyloxy-4-methoxyphenyl)ethylideneamino] carbamate
Synonyms	Filaminast (USAN/INN) FIL Way-pda-641 (1E)-1-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]ETHANONE O-(AMINOCARBONYL)OXIME FILAMINAST UNII-CDD69JC61J

Description	WAY-PDA 641 is a potent and preferential PDE-IV inhibitor, with an IC50 of 0.42 μM for canine trachealis PDE-IV. WAY-PDA 641 induces respiratory muscle relaxation and bronchodilation[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology
References	[1]. Heaslip RJ, et, al. Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641. J Pharmacol Exp Ther. 1994 Feb;268(2):888-96.