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21392-57-4

21392-57-4 structure
21392-57-4 structure
  • Name: Chrysin dimethylether
  • Chemical Name: chrysin 5,7-dimethyl ether
  • CAS Number: 21392-57-4
  • Molecular Formula: C17H14O4
  • Molecular Weight: 282.291
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-06-08 12:30:53
  • Modify Date: 2024-01-02 10:02:17
  • 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].

Name chrysin 5,7-dimethyl ether
Synonyms 5,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one
Dimethylchrysin
Chrysin DME
5,7-dimethoxyflavonone
MFCD00016943
2-phenyl-5,7-dimethoxyl-flavone
4H-1-Benzopyran-4-one,5,7-dimethoxy-2-phenyl
Chrysin 5,7-dimethyl ether
4H-1-Benzopyran-4-one, 5,7-dimethoxy-2-phenyl-
5,7-DIMETHOXYFLAVONE
5,7-dimethoxy-2-phenylchromen-4-one
5,7-dimethoxycrysin
5,7-dimethoxy-2-phenyl-chromen-4-one
5,7-Dimethoxy-2-phenyl-4H-chromen-4-one
Chrysindimethylether
Chrysin dimethylether
Description 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].
Related Catalog
Target

CYP3A

Breast Cancer Resistance Protein (BCRP)

References

[1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614.

[2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34.

Density 1.2±0.1 g/cm3
Boiling Point 476.6±45.0 °C at 760 mmHg
Melting Point 150-152ºC
Molecular Formula C17H14O4
Molecular Weight 282.291
Flash Point 213.4±28.8 °C
Exact Mass 282.089203
PSA 48.67000
LogP 3.27
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.598
HS Code 2914509090
HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%