1262776-24-8

1262776-24-8 structure
1262776-24-8 structure
  • Name: Clothianidine-d3
  • Chemical Name: 2-[(2-chloro-1,3-thiazol-5-yl)methyl]-1-nitro-3-(trideuteriomethyl)guanidine
  • CAS Number: 1262776-24-8
  • Molecular Formula: C6H5ClD3N5O2S
  • Molecular Weight: 252.697
  • Catalog: Research Areas Others
  • Create Date: 2018-07-29 18:03:14
  • Modify Date: 2024-01-03 08:20:59
  • Clothianidin-d3 is the deuterium labeled Clothianidin.

Name 2-[(2-chloro-1,3-thiazol-5-yl)methyl]-1-nitro-3-(trideuteriomethyl)guanidine
Synonyms 1-[(2-chlorothiazol-5-yl)methyl]-2-nitro-3-(trideuteriomethyl)guanidine
1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-(H)methyl-3-nitroguanidine
Clothianidin-d3
Clothianidine-d3
(E)-1-(2-Chloro-5-thiazolylmethyl)-3-(methyl-d3)-2-nitroguanidine
Guanidine, N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-d-N''-nitro-
Description Clothianidin-d3 is the deuterium labeled Clothianidin.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Density 1.7±0.1 g/cm3
Boiling Point 435.2±55.0 °C at 760 mmHg
Molecular Formula C6H5ClD3N5O2S
Molecular Weight 252.697
Flash Point 217.0±31.5 °C
Exact Mass 252.027557
PSA 123.37000
LogP -0.15
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.709
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H410
Precautionary Statements P273-P501
RIDADR UN 3077 9 / PGIII