284474-50-6

284474-50-6 structure
284474-50-6 structure
  • Name: 1-(4-Chlorophenyl)ethanone-d4
  • Chemical Name: 1-(4-chloro-2,3,5,6-tetradeuteriophenyl)ethanone
  • CAS Number: 284474-50-6
  • Molecular Formula: C8H3ClD4O
  • Molecular Weight: 158.61800
  • Catalog: Research Areas Others
  • Create Date: 2019-01-15 10:30:44
  • Modify Date: 2024-01-09 11:38:52
  • 1-(4-Chlorophenyl)ethanone-d4 is the deuterium labeled 1-(4-Chlorophenyl)ethanone[1].

Name 1-(4-chloro-2,3,5,6-tetradeuteriophenyl)ethanone
Synonyms MFCD00084129
4'-Chloroacetophenone-2',3',5',6'-d4
4 inverted exclamation marka-Chloroacetophenone-2 inverted exclamation marka,3 inverted exclamation marka,5 inverted exclamation marka,6 inverted exclamation marka-d4
Description 1-(4-Chlorophenyl)ethanone-d4 is the deuterium labeled 1-(4-Chlorophenyl)ethanone[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Density 1.192 g/mL at 25ºC
Boiling Point 232ºC(lit.)
Melting Point 14-18ºC(lit.)
Molecular Formula C8H3ClD4O
Molecular Weight 158.61800
Flash Point 194 °F
Exact Mass 158.04400
PSA 17.07000
LogP 2.54260
Index of Refraction n20/D 1.5549(lit.)
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H302-H315-H318-H330-H335
Precautionary Statements P260-P280-P284-P305 + P351 + P338-P310
Hazard Codes Xn: Harmful;
Risk Phrases 22-36/37/38
Safety Phrases 26-27-36/37/39-45
RIDADR UN 3416 6.1/PG 2