17598-96-8

17598-96-8 structure
17598-96-8 structure
  • Name: HO-PEG13-OH
  • Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • CAS Number: 17598-96-8
  • Molecular Formula: C26H54O14
  • Molecular Weight: 590.69900
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-08-08 08:05:09
  • Modify Date: 2024-01-09 17:58:19
  • HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatriacontane-1,38-diol
tridecaethylene glycol
EINECS 241-569-7
Description HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.116g/cm3
Boiling Point 631.6ºC at 760mmHg
Molecular Formula C26H54O14
Molecular Weight 590.69900
Exact Mass 590.35100
PSA 151.22000
Vapour Pressure 1.32E-18mmHg at 25°C
Index of Refraction 1.465
HS Code 2909499000
HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%